Salvage surgery for childhood osteosarcoma

  • Ugo Pastorino
  • Marco Gasparini
  • Alberto Azzarelli
  • Luca Tavecchio
  • Gianni Ravasi
Part of the Cancer Treatment and Research book series (CTAR, volume 62)


The concept of salvage surgery in osteosarcoma is based on solid knowledge of the natural history of this disease. Unlike many other solid tumors, sarcomas manifest the peculiar characteristic of organ-restricted spread [1,2]. In most cases, lung metastases are the only site of distant relapse, occurring in 50–80% of osteosarcomas [1,3]. Although, if the cure rates for childhood osteosarcoma have dramatically improved over the last 20 years, lung metastases still remain a major cause of failure, occurring in 40–50% of patients [4] and being refractory to salvage chemotherapy [5, 6, 7]. A summary of the reported results of salvage surgery in osteosarcoma is given in Table 30-1 [8, 9, 10, 11, 12, 13, 14, 15].


Clin Oncol Lung Metastasis Pulmonary Metastasis Median Sternotomy Salvage Surgery 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • Ugo Pastorino
    • 1
  • Marco Gasparini
    • 2
  • Alberto Azzarelli
    • 3
  • Luca Tavecchio
  • Gianni Ravasi
    • 1
  1. 1.Division of Thoracic SurgeryNational Tumor InstituteMilanItaly
  2. 2.Pediatric OncologyNational Tumor InstituteMilanItaly
  3. 3.General Surgery ANational Tumor InstituteMilanItaly

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