Small cell osteosarcoma

  • Alberto G. Ayala
  • Jae Y. Ro
  • Nicholas K. Papadopoulos
  • A. Kevin Raymond
  • Jack Edeiken
Part of the Cancer Treatment and Research book series (CTAR, volume 62)


Small cell osteosarcoma (SCO) is a rare but distinct variant of osteosarcoma. Although Hutter et al. [1] in 1966 and Jacobson in 1977 [2] described small cell tumors of bone capable of differentiating into bone and cartilage, Sim and collaborators [3], reporting in 1979 on 24 patients at the Mayo Clinic, were the first to delineate the clinicopathological features of this entity. Further clarification was given by other investigators [4, 5, 6, 7], but few large series of patients with these lesions have been studied [3, 4, 5, 6, 7], and there have been only several case reports [8, 9, 10] of these lesions.


Neuroectodermal Tumor Medullary Cavity Mesenchymal Chondrosarcoma Small Cell Tumor Conventional Osteosarcoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • Alberto G. Ayala
    • 1
  • Jae Y. Ro
    • 1
  • Nicholas K. Papadopoulos
    • 2
  • A. Kevin Raymond
    • 1
  • Jack Edeiken
    • 3
  1. 1.Department of PathologyMD Anderson Cancer Center and University of TexasHoustonUSA
  2. 2.Medical OncologyMD Anderson Cancer Center and University of TexasHoustonUSA
  3. 3.Diagnostic RadiologyMD Anderson Cancer Center and University of TexasHoustonUSA

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