Advertisement

Usefulness of Exercise T1-201 Myocardial Scintigraphy to Detect Asymptomatic Heart Disease in Diabetic Patients

  • K. Kawakami
  • I. Yasuda
  • T. Shimada
  • R. Murakami
  • S. Morioka
  • K. Tanigawa
  • Y. Kato
  • K. Moriyama
Part of the Developments in Cardiovascular Medicine book series (DICM, volume 130)

Abstract

Diabetes mellitus is thought to be one of the risk factors of coronary heart disease (1,2). It is hard to detect ischemic heart disease in diabetic patients because many of them are asymptomatic. It is also considered that cardiomyopathy more often occurs in diabetic patients than in normal population (3,4,5). Exercise Tl-201 scintigraphy are commonly used to detect myocardial viability in coronary heart disease (6,7,8) and cardiomyopathy (9). We evaluate how often the patients of diabetes mellitus without symptoms suffer from heart disease, using the scintigraphic method.

Keywords

Single Photon Emission Compute Tomography Perfusion Defect Diabetic Cardiomyopathy Myocardial Scintigraphy Coronary Arteriography 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Marks HH, Krall LP. Onset, course prognosis in diabetes mellitus. In: Diabetes Mellitus (eds.) Marble A, White P, Bradley RF, Krall LP. Philadelphia, Lea & Febiger; 1971:226.Google Scholar
  2. 2.
    Bradley RF. Cardiovascular disease. In: Joslin’sDiabetes Mellitus (eds.) Marble A, White P, Bradley RF, IKrall L. Philadelphia, Lea & Febiger;1971:419.Google Scholar
  3. 3.
    Blumenthal HT, Alex M, Goldenberg S. A study of lesions of the intramural coronary artery branches in diabetic mellitus. Arch Pathol 1960;70:13.Google Scholar
  4. 4.
    Rubier S, Dlugash J, Yuceoglu YZ, Kumal T, Branwood AM, Grishman A. New type of cardiomyopathy associated with diabetic glomerulosclerosis. Am J Cardiol 1972;30:595.CrossRefGoogle Scholar
  5. 5.
    Hamby RI, Zoneraich S, Sherman L. Diabetic cardiomyopathy. JAMA 1974;229:1749.PubMedCrossRefGoogle Scholar
  6. 6.
    Kawakami K, Yasuda I, Shimada T, Murakami M, Morioka S, Moriyama K. Re-evaluation of Bullseye map in the patient with coronary heart disease. Jpn J Nuc Med 1989;26:921.Google Scholar
  7. 7.
    Richie JL, Zaret BJ, Strauss HW, Pitt B, Berma DS, Sherbert HW, Ashburn WN, Berger HJ, Hamiltom GW. Myocardial imaging with thallium-201: A multicenter study in patients with angina pectoris or acute myocardial infarction. Am J Cardiol 1978;42:345.CrossRefGoogle Scholar
  8. 8.
    De Pasquale ED, Nody AC, De Puey EG, Garcia EV, Pilcher G, Bledlau C, Roubin G, Gober A, Gluentzig A, D’Amato P, Berger HJ. Quantitative rotational thallium-201 tomography for identifying and localizing coronary artery disease. Circulation 1988;77(2):316.CrossRefGoogle Scholar
  9. 9.
    O’sGara PT, Bonow RO, Marson BJ, Damske BA, Lingen AV, Bacharash SL, Larson SM, Epstein SE. Myocardial perfusion abnormalities in patients with hypertrophic cardiomyopathy assessment with thaliium-201 emission tomography. Circ 1987;76:6.CrossRefGoogle Scholar
  10. 10.
    Hilsted J, Galvo H, Christensen NJ. Impaired cardiovascular responses to graded exercise in diabetic autonomic neuropathy. Diabetes 1979;28:313.PubMedCrossRefGoogle Scholar
  11. 11.
    Storstein L, Jervell J. Response to the bicycle exercise testing in longstanding juvenile diabetes. Acta Med Scand 1979;205:227.PubMedCrossRefGoogle Scholar
  12. 12.
    Airaksinen JKE, Kaila JM, Linnaluoto MK, Ikaheimo MJ, Takkunen JT. Cardiovascular response to exercise in young woman with insulin-dependent diabetes mellitus. Acta diabetol lat 1985;22:1.PubMedCrossRefGoogle Scholar
  13. 13.
    Abenaboli TJ, Ruber S, Fisher VJ, Axelrod HI, Zucherman KP. Exercise testing with myocardial scintigraphy in asymptomatic diabetic males. Circulation 1981;63:54.CrossRefGoogle Scholar
  14. 14.
    Mizuno S, Genda A, Nakayama A, Igarashi Y, Takeda R. Myocardial involvement in diabetic patients evaluated by exercise thallium-201 scintigraphy and cardiac catheterization. J Cardiography 1985;15:427.Google Scholar
  15. 15.
    Amano K, Sakamoto T, Oku J, Fujinami J, Sugimoto T. Diabetic cardiomyopathy: the relationship between 201-thallium myocardial scintigraphic perfusion defect and left ventricular function in symptomatic diabetes. Acta Cardiologica 1988;18(2):75.Google Scholar
  16. 16.
    Kannel WB, Hjortland M, Castelli WP. Role of diabetes in congestive heart failure: The Framingham Study. Am J Cardiol 1974;34:29.PubMedCrossRefGoogle Scholar
  17. 17.
    Regan TJ, Lyons MM, Ahmed SS, Levinson GE, Oldewurtel HA, Ahmed MR, Haider B. Evidence for cardiomyopathy in familial diabetes mellitus. J Clin Inv 1977;60:885.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1992

Authors and Affiliations

  • K. Kawakami
    • 1
  • I. Yasuda
    • 1
  • T. Shimada
    • 1
  • R. Murakami
    • 1
  • S. Morioka
    • 1
  • K. Tanigawa
    • 1
  • Y. Kato
    • 1
  • K. Moriyama
    • 1
  1. 1.The Fourth Department of Internal MedicineShimane Medical UniversityIzumo-city, Shimane-prefectureJapan

Personalised recommendations