Interpretation of Endothelial Structure Related to Tumor and Atherosclerotic Blood Vessels

  • James G. Walmsley
Part of the Electron Microscopy in Biology and Medicine book series (EMBM, volume 10)


Scanning electron microscopy (SEM) of vascular corrosion casts provides an opportunity to gain specific information about the luminal cellular lining of blood conduits. In addition to observation of the pattern, distribution, and density of this cellular layer, more subtle changes may be detectable. However, the determination of any of this information requires appropriate preparative procedures for highlighting the features being evaluated. For the purposes of this chapter, the discussion is primarily limited to the cellular lining of blood vessels, the vascular endothelium, and the alterations that are associated with experimental tumors and atherosclerosis. It is then possible to use the proper interpretation of endothelial surface structure to comment on the disease process itself.


Fatty Streak Rabbit Aorta Volume Orientation Hypercholesterolemic Rabbit Avascular Zone 
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Copyright information

© Springer Science+Business Media New York 1992

Authors and Affiliations

  • James G. Walmsley
    • 1
  1. 1.Department of Biomedical SciencesUniversity of Illinois College of Medicine at RockfordRockfordUSA

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