Taurine pp 319-328 | Cite as

Taurine Protection of Lungs in Hamster Models of Oxidant Injury: A Morphologic Time Study of Paraquat and Bleomycin Treatment

  • Ronald E. Gordon
  • Richard F. Heller
  • Rachel F. Heller
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 315)


The intracellular reduction of oxygen is a natural part of nutrient conversion into energy and results in the production of small amounts of short-lived intermediates of oxygen; superoxide [O2-], singlet oxygen [1O2],hydrogen peroxide [H2O2] and hydroxide radical [OH]1. Naturally occurring enzymatic “scavengers” serve as the primary protection against oxidant injury2. When the production of oxygen intermediates exceeds the scavenging and detoxifying capacity of these enzymes, then lung parenchymal cell injury results3.


Pulmonary Fibrosis Interstitial Fibrosis Light Micrograph Intratracheal Instillation Taurine Supplementation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1992

Authors and Affiliations

  • Ronald E. Gordon
    • 1
  • Richard F. Heller
    • 1
  • Rachel F. Heller
    • 1
  1. 1.Department of Pathology - Box 1194Mount Sinai School of MedicineNew YorkUSA

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