Abstract
We are studying dietary taurine deficiency in developing rhesus monkeys in order to define its biochemical, morphological and functional effects and their timing and reversibility. Given the similarity between human and rhesus monkey infants in their nutritional requirements, sensory capacities and nervous system structure and function, these studies provide the best available model for assessing the long-term importance of dietary taurine for the development of the human retina and brain.
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References
Boothe, R.G., Dobson, V., and Teller, D.Y., 1985, Postnatal development of vision in human and non-human primates, Ann. Rev. Neurosci. 8:495–545.
Gault, G.E., Rassin, D.K., and Sturman, JA., 1969, Enzymatic and metabolic studies of homocystinuria: effects of pyridoxine, Neuropadiatrie 1:199–226.
Imaki, H, Moretz, R., Wisniewski, H., Neuringer, M., and Sturman, J., 1987, Retinal degeneration in 3-month-old rhesus monkey infants fed a taurine-free human infant formula, J. Neurosci. Res. 18:602–614.
Imaki, H., Sturman, J., and Neuringer, M., 1991, Retinal morphology in rhesus monkeys fed formula with and without taurine for 6 and 12 months, Invest. Ophthalmol. Vis. Sci. 32:1231 (abstract).
Misra, C.H., and Olney, J.W., 1975, Cysteine oxidase in brain, Brain Res. 97:117–126.
Neuringer, M., Palackal, T., Kujawa, M., Moretz, R.C., and Sturman, JA., 1990, Visual cortex development in rhesus monkeys deprived of dietary taurine, in: “Taurine: Functional Neurochemistry, Physiology and Cardiology,” H. Pasantes-Morales, D.L. Martin, W. Shain, and R. Martin del Rio, eds., Wiley-Liss, New York, pp. 415–422.
Neuringer, M., and Sturman, JA., 1987, Visual acuity loss in rhesus monkey infants fed a taurine-free human infant formula, J. Neurosci. Res. 18:597–601.
Neuringer, M., Sturman, JA., Wen, G.Y., and Wisniewski, H.M., 1985, Dietary taurine is necessary for normal retinal development in monkeys, in: “Taurine: Biological Actions and Clinical Perspectives,” S.S. Oja, L. Ahtee, P. Kontro, and M.K. Paasonen, eds., Alan R. Liss, New York, pp. 53–62.
Palackal, T., Kujawa, M., Moretz, R.C., Neuringer, M., and Sturman, JA., 1991, Laminar analysis of the number of neurons, astrocytes, oligodendrocytes and microglia in the visual cortex (area 17) of 3-month-old rhesus monkeys fed a human infant soy-protein formula with or without taurine supplementation from birth, Dev. Neurosci. 13:20–33.
Rabin, B., Nicolosi, R.J., and Hayes, K.C., 1976, Dietary influence on bile acid conjugation in the cat, J. Nutr. 106:1241–1246.
Rassin, D.K., Sturman, JA., and Gaull, G.E., 1978, Taurine and other free amino acids in milk of man and other mammals, Early Hum. Dev. 2:1–13.
Rossi, S.S., Converse, J.L., and Hofmann, A.E., 1987, High pressure liquid chromatographic analysis of conjugated bile acids in human bile: simultaneous resolution of sulfated and unsulfated lithocholyl amidates and the common conjugated bile acids, J. Lipid Res. 28:589–595.
Sturman, JA., Gargano, A.D., Messing, J.M., and Imaki, H., 1986, Feline maternal taurine deficiency: effect on mother and offspring., J. Nutr. 116:655–667.
Sturman, JA, and Gaull, G.E., 1975, Taurine in the brain and liver of the developing human and monkey, J. Neurochem. 25:831–835.
Sturman, JA., Messing, J.M., Rossi, S.S., Hofmann, A.F., and Neuringer, M., 1988, Tissue taurine content and conjugated bile acid composition of rhesus monkey infants fed a human infant soy-protein formula with or without taurine supplementation for three months, Neurochem. Res. 13:311–316.
Sturman, JA., Messing, J.M., Rossi, S.S., Hofmann, A.F., and Neuringer, M., 1991, Tissue taurine content, activity of taurine synthesis enzymes and conjugated bile acid composition of taurine-deprived and taurine-supplemented rhesus monkey infants at 6 and 12 months of age,J. Nutr. 121:854–862.
Sturman, JA., Wen, G.Y., Wisniewski, H., and Neuringer, M., 1984, Retinal degeneration in primates raised on a synthetic human infant formula, Int. J. Devel. Neurosci. 2:121–129.
Yamaguchi, K., Sakakibara, S., Asamizu, J., and Ueda, I., 1973, Induction and activation of cysteine oxidase of rat liver. II. The measurement of cysteine metabolism in vivo and the activation of in vivo activity of cysteine oxidase, Biochim. Biophys. Acta 297:48–59.
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Neuringer, M., Sturman, J.A., Imaki, H., Palackal, T. (1992). Regression of Taurine Depletion in Rhesus Monkeys Deprived of Dietary Taurine throughout the First Year. In: Lombardini, J.B., Schaffer, S.W., Azuma, J. (eds) Taurine. Advances in Experimental Medicine and Biology, vol 315. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3436-5_24
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DOI: https://doi.org/10.1007/978-1-4615-3436-5_24
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