Proposal for Patient Selection Criteria and Follow-Up for BNCT in Patients with Supratentorial Malignant Gliomas
Treatment beam and irradiation room of the High Flux reactor in Petten are close to completion and pre-clinical dog irradiation studies were started in summer 1991. It is therefore timely to draft the preliminary protocol which will be applied to the initial patient study using borocaptate sodium (BSH) and epithermal neutrons for the treatment of malignant gliomas. At this stage emphasis is put on inclusion criteria, follow-up, and data collection, rather than on details of BNCT itself. The latter are to be finalized once the results of the irradiation at the treatment position of normal dogs with and without intravenously administered BSH are available.
KeywordsTransportation Boron Astrocytoma Oligodendroglioma
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