Changes in Tissue Histology Associated with Adaptation and Acclimation to Hypoxia
The terms adaptation and hypoxia are both widely used but not always with quite the same meanings. Now that it is possible to measure the partial pressure of oxygen in every part of the mammalian organism with a fair degree of accuracy and a high degree of spatial resolution it seems appropriate to define hypoxia as a partial pressure of oxygen significantly lower than that normally found in that part of the organism. Thus an inspired Po2 of much less than 150 Torr and a Lubbers histogram of tissue oxygen tensions shifted to the left would both be defined as hypoxia.
KeywordsOxygen Consumption Liver Slice Tissue Oxygen Tension Mammalian Organism Reduce Oxygen Consumption
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- Longmuir, I.S. and Moore, R.E. (1957). The change with age in the critical oxygen concentration of kitten liver slices. J. Physiol. 138, 44.Google Scholar
- Moore, R.E. (1956). Loss with age of kittens’ adaptation to hypoxia. J. Physiol. 133, 60–70.Google Scholar
- Weibel, E.R. and Elias, H. (1967). Introduction to stereo logic principles. In: Quantitative Methods in Morphology. Eds Weibel, E.R. and Elias, H. Springer-Verlag, Berlin, pp. 89–98.Google Scholar