Photodynamic Therapy of Brain Tumours
Cerebral tumours are responsible for approximately 2% of all cancer deaths and the high grade cerebral glioma is the most common cerebral tumour in adults. At the present time there is no satisfactory treatment for the malignant cerebral glioma. The best available treatment, using surgery, radiation therapy and systemic chemotherapy results in a median survival time of less than one year (Walker et al 1978; Walker et al 1980). In most cases surgery only provides a histological confirmation of the diagnosis and provides palliation of symptoms of raised intracranial pressure. Radiotherapy prolongs the median survival to 37 weeks and at present chemotherapy is of limited value when given by either conventional or the intracarotid route. Most treatment failures occur because of local recurrence of the tumour, indicating that a more aggressive local therapy to the tumour could be beneficial for the treatment of gliomas.
KeywordsBoron Neurol Psoriasis Porphyrin Mannitol
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