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In Vitro Models of Implantation

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Uterine and Embryonic Factors in Early Pregnancy

Part of the book series: Reproductive Biology ((RBIO))

Abstract

Blastocysts are capable of attaching to a uterus only after it has been appropriately prepared by ovarian steroid hormones (receptive uterus). 1,2 They can, however, attach to extrauterine sites regardless of the hormonal environment.3 These data suggest that under certain conditions the apical surface of the uterine epithelial (UE) cell expresses molecules (ligands) which do not permit blastocyst attachment (non-receptive). It has been proposed that interactions between UE cells and various regulatory agents (hormones, growth factors) effect (induce, stimulate, repress) structural and functional changes at the apical surface of the UE cell that allow nidation.

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Authors and Affiliations

  1. Department of Cell Biology and the Center for Population Research and Studies in Reproductive Biology, Baylor College of Medicine, Houston, Texas, 77030, USA

    Stanley R. Glasser, Shailaja K. Mani & Joy Mulholland

Authors
  1. Stanley R. Glasser
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  2. Shailaja K. Mani
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  3. Joy Mulholland
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Editors and Affiliations

  1. University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA

    Jerome F. Strauss III  & C. Richard Lyttle  & 

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© 1991 Springer Science+Business Media New York

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Glasser, S.R., Mani, S.K., Mulholland, J. (1991). In Vitro Models of Implantation. In: Strauss, J.F., Lyttle, C.R. (eds) Uterine and Embryonic Factors in Early Pregnancy. Reproductive Biology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3380-1_5

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  • DOI: https://doi.org/10.1007/978-1-4615-3380-1_5

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6492-4

  • Online ISBN: 978-1-4615-3380-1

  • eBook Packages: Springer Book Archive

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