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The Functional Role of T-Tubular Calcium Channels in Skeletal Muscle Contractions

  • George B. Frank
  • Murat Öz
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 311)

Abstract

Nearly 35 years ago, when I began my studies on the role of calcium ions in excitation-contraction (e-c) coupling in skeletal muscle there seemed to be excellent evidence supporting the concept that the e-c coupling process was identical during twitches and depolarization contractures (Frank, 1961). For this reason in my initial studies I used high K+-induced contractures in a Na+-free solution as a model for the events occurring during e-c coupling in both types of muscle activity (Frank, 1958, 1960).

Keywords

Skeletal Muscle Sarcoplasmic Reticulum Skeletal Muscle Fiber Charge Movement Stimulus Train 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1992

Authors and Affiliations

  • George B. Frank
    • 1
  • Murat Öz
    • 1
  1. 1.Department of PharmacologyUniversity of AlbertaEdmontonCanada

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