Modulation of L-Type Calcium Current in Mammalian Ventricular Myocytes by Photolysis of Caged Calcium

  • Susan E. Bates
  • Alison M. Gurney
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 311)

Abstract

The caged calcium compound nitr-5 was used to investigate the effects of a rapid increase in intracellular calcium concentration on the L-type calcium current (ICa) of guinea pig ventricular cells. Short term inactivation and longer lasting potentiation were observed.

Keywords

Cage CaCl2 HEPES Photolysis Xenon 

References

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Copyright information

© Springer Science+Business Media New York 1992

Authors and Affiliations

  • Susan E. Bates
    • 1
  • Alison M. Gurney
    • 1
  1. 1.Department of Pharmacology UMDSSt. Thomas’s HospitalLondonEngland

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