Endothelium-Dependent and-Independent Relaxation of Aortas from Copper-Deficient Rats
Isolated aortas from copper-deficlent rats exhibited reduced ability to relax in response to acetylcholine, histamine and sodium nitroprusside, which suggests that release of endothelium-derived relaxing factor or its interaction with the contractile mechanism is impaired.
KeywordsSodium Nitroprusside Guanylate Cyclase Relaxation Response Toxic Trace Element Contractile Mechanism
Unable to display preview. Download preview PDF.
- 5.J. R. Prohaska, Biochemical functions of copper in animals, in: “Essential and Toxic Trace Elements in Human Health and Disease,” A. S. Prasad, ed., Alan R Liss, Inc., New York, pp. 105–124 (1988).Google Scholar