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Ca2+ Influx Through Voltage- and Purinoceptor-Operated Channels Estimated from [Ca2+]C Signals (Myocytes from Guinea-Pig Urinary Bladder)

  • G. Isenberg
  • V. Ya. Ganitkevich
  • P. Schneider
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 311)

Summary

The rise in free cytosolic calcium was studied by a combination of the techniques of microspectrofluorometry and whole-cell patch clamp. By comparing the membrane currents with their effect on [Ca2+]c, the relative importance of Ca2+ influx could be quantified for both L-type Ca2+ channels and non-selective channels activated by extracellular ATP.

Keywords

Succinic Acid Membrane Current Sustained Level Bath Application Free Cytosolic Calcium 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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    CD. Benham, J. Physiol., 419:689–701 (1989).PubMedGoogle Scholar
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    V.Ya Ganitkevich, and G. Isenberg, J. Physiol. 435:187–207 (1991).Google Scholar
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    G. Grynkiewicy, M. Ponie, and R.Y. Tsien, J. Biol. Chem. 260:3440–3450.Google Scholar

Copyright information

© Springer Science+Business Media New York 1992

Authors and Affiliations

  • G. Isenberg
    • 1
  • V. Ya. Ganitkevich
    • 1
  • P. Schneider
    • 1
  1. 1.Department of PhysiologyUniversity of CologneGermany

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