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Action of Vasoconstrictor Hormones and Calcium Entry Modulators on Electrical Activity and Intracellular Calcium of Smooth Muscle Cells

  • U. T. Ruegg
  • H. J. Knot
  • M. M. de Ree
  • B. H. Gahwiler
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 311)

Abstract

The A7r5 smooth muscle cell line, which was originally derived from rat aorta, was studied. These cells show a spontaneous electrical activity. Resting membrane potential was about -45mV. The cells displayed spontaneous overshooting acting potentials at a frequency of 0.1 to 0.5 Hz.

Keywords

Smooth Muscle Cell Electrical Activity Rest Membrane Potential Calcium Entry Entry Blocker 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Springer Science+Business Media New York 1992

Authors and Affiliations

  • U. T. Ruegg
    • 1
  • H. J. Knot
    • 1
  • M. M. de Ree
    • 1
  • B. H. Gahwiler
    • 2
  1. 1.Preclinical ResearchSandoz Pharma LtdBasleSwitzerland
  2. 2.Brain Research InstituteUniversity of ZurichZurichSwitzerland

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