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Role of Calcium Channels of the Sarcolemma and the Sarcoplasmic Reticulum in Skeletal Muscle Functions

  • C. Paul Bianchi
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 311)

Abstract

Calcium channels of the sarcolemma and the sarcoplasmic reticulum play a key integrative role in determining and fine tuning the ionic free calcium concentration of the sarcoplasm and regulation of muscle function. Changes in the free ionic calcium concentration can lead to (1) force development and motion, (2) heat production during fever, and (3) breakdown of muscle protein reserves.

Keywords

Sarcoplasmic Reticulum Calcium Influx Extractable Calcium Transverse Tubule Dihydropyridine Receptor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1992

Authors and Affiliations

  • C. Paul Bianchi
    • 1
  1. 1.Dept. of Pharmacology, Jefferson Medical CollegeThomas Jefferson UniversityPhiladelphiaUSA

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