Role of Calcium Channels of the Sarcolemma and the Sarcoplasmic Reticulum in Skeletal Muscle Functions
Calcium channels of the sarcolemma and the sarcoplasmic reticulum play a key integrative role in determining and fine tuning the ionic free calcium concentration of the sarcoplasm and regulation of muscle function. Changes in the free ionic calcium concentration can lead to (1) force development and motion, (2) heat production during fever, and (3) breakdown of muscle protein reserves.
KeywordsSarcoplasmic Reticulum Calcium Influx Extractable Calcium Transverse Tubule Dihydropyridine Receptor
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