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Na/Ca Exchange and First Messenger Ca in Skeletal Muscle Excitation - Contraction Coupling

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Excitation-Contraction Coupling in Skeletal, Cardiac, and Smooth Muscle

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 311))

Abstract

Depolarization initiates a process in the wall of the transverse tubular system (t system). This process gives rise to a transient electrical signal - charge movement - which is closely linked to the release of Ca from the sarcoplasmic reticulum (SR) via the foot process. Two types of linkage have been discussed at this Conference: 1) structural links spanning the t-SR gap, such as the rigid rod model (Schneider and Chandler, 1973), and 2) chemical links including trigger Ca (Bianchi, 1969 and Frank, 1980).

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Author information

Authors and Affiliations

  1. University of Illinois College of Medicine at Peoria, Peoria, IL, 61656, USA

    Brian A. Curtis

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  1. Brian A. Curtis
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Editor information

Editors and Affiliations

  1. University of Alberta, Edmonton, Alberta, Canada

    George B. Frank

  2. Thomas Jefferson University, Philadelphia, Pennsylvania, USA

    C. Paul Bianchi

  3. University of Calgary, Calgary, Alberta, Canada

    Henk E. D. J. ter Keurs

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© 1992 Springer Science+Business Media New York

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Curtis, B.A. (1992). Na/Ca Exchange and First Messenger Ca in Skeletal Muscle Excitation - Contraction Coupling. In: Frank, G.B., Bianchi, C.P., ter Keurs, H.E.D.J. (eds) Excitation-Contraction Coupling in Skeletal, Cardiac, and Smooth Muscle. Advances in Experimental Medicine and Biology, vol 311. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3362-7_1

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  • DOI: https://doi.org/10.1007/978-1-4615-3362-7_1

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6483-2

  • Online ISBN: 978-1-4615-3362-7

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