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Mechanisms of Embryonic Blood Vessel Formation

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Angiogenesis in Health and Disease

Part of the book series: NATO ASI Series ((NSSA,volume 227))

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Abstract

All blood vessels develop form angioblasts which differentiate in the early embryonic mesoderm of the area pellucida and area opaca. The mechanisms of angioblast induction are still unknown but the participation of the endoderm in this induction event seems to be a prerequisite (1). One model system to study the early development of the vascular system are embryonic stem cells, which in suspension culture spontaneously differentiate into angioblast-containing cystic embryoid bodies. This process apparently in an inherent program of embryonic stem cell differentiation (2).

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References

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Authors and Affiliations

  1. MaxPlank Institut fur Psychiatrie, Abt. Neurochemie, Am Klopferspitz 18A, 8033, Martinstried, Germany

    H. Drexler, H. Schurch, G. Breier, G. Drexler & W. Risau

Authors
  1. H. Drexler
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  2. H. Schurch
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  3. G. Breier
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  4. G. Drexler
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  5. W. Risau
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Editor information

Editors and Affiliations

  1. University of Patras Medical School, Patras, Greece

    Michael E. Maragoudakis

  2. University of Turin Medical School, Turin, Italy

    Pietro Gullino

  3. University of Wisconsin Medical School, Milwaukee, Wisconsin, USA

    Peter I. Lelkes

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© 1992 Springer Science+Business Media New York

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Drexler, H., Schurch, H., Breier, G., Drexler, G., Risau, W. (1992). Mechanisms of Embryonic Blood Vessel Formation. In: Maragoudakis, M.E., Gullino, P., Lelkes, P.I. (eds) Angiogenesis in Health and Disease. NATO ASI Series, vol 227. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3358-0_33

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  • DOI: https://doi.org/10.1007/978-1-4615-3358-0_33

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6481-8

  • Online ISBN: 978-1-4615-3358-0

  • eBook Packages: Springer Book Archive

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