Mother-to-Fetus/Infant Transmission of HIV-1: Scientific Evidence and Research Needs
In less than two decades, the HIV virus has spread throughout the world, with virtually every country reporting cases of HIV infection to the World Health Organization (WHO) by 1990. It is remarkable how quickly researchers identified the HIV virus and its basic characteristics and structure, major modes of transmission, pathogenic mechanisms, and the symptoms and signs of HIV infection. But only recently has transmission from infected mothers to their fetuses and infants attracted the attention it deserves from the scientific community.
KeywordsHuman Immunodeficiency Virus Human Immunodeficiency Virus Type Passive Immunization Perinatal Transmission Infected Mother
Unable to display preview. Download preview PDF.
- 6.Bledsoe K, Olopoenia L, Barnes S et al. Effect of pregnancy on progression of HIV infection. Sixth International Conference on AIDS, San Francisco, CA, June 1990; Abstract Th.C.652.Google Scholar
- 9.European Collaborative Study. Mother-to-child transmission of HIV infection. Lancet 1988; i:1039–1043.Google Scholar
- 10.Freij BJ and Sever JL. Herpesvirus infections in pregnancy: Risk to embryo, fetus and neonate. Clin perinatal 1988; 15:203–230.Google Scholar
- 16.Italian Multicentre Study. Epidemiology, clinical features, and prognostic factors of paediatric HIV infection. Lancet 1988; ii:1043–46.Google Scholar
- 17.Jovaisas E, Koch MA, Schaafer A et al. LAV/HTLV III in 20-week fetus. Lancet 1985; ii:1129.Google Scholar
- 21.Marion RW, Wiznia AA, Hutcheon RG et al. Fetal AIDS syndrome score: Correlation between severity of dysmorphism and age at diagnosis of immunodeficiency. Am J Dis Chil 1987; 141:429–431.Google Scholar
- 24.Olness K, personal communication, 1990.Google Scholar
- 29.Terragna A, Anselmo M, Camera M et al. Influence of pregnancy on disease progression in 31 HIV infected patients. Conference on the Implications of AIDS for Mother and Children, November 27–30, 1989, Paris, France; Abstract E2.Google Scholar
- 31.World Health Organization. Statement from the consultation on breast-feeding/breast milk and Human Immunoefficiency virus (HIV). World Health Organization, Geneva, 1987.Google Scholar