The Concept of Direct and Indirect Neurotoxicity and the Concept of Toxic Metal/Essential Element Interactions as a Common Biomechanism Underlying Metal Toxicity

  • Louis W. Chang


The toxicities of many metals have been well defined. Many of these metals, such as mercury, lead, cadmium, manganese, aluminum, and alkyltin, have demonstrated a special target affinity towards the nervous system.


Dorsal Root Ganglion Lesion Development Cadmium Toxicity Lead Toxicity Dentate Granule Cell 
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Copyright information

© Springer Science+Business Media New York 1992

Authors and Affiliations

  • Louis W. Chang
    • 1
  1. 1.Departments of Pathology, Pharmacology, and ToxicologyUniversity of Arkansas for Medical SciencesLittle RockUSA

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