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Alcohol Abuse: Carcinogenic Effects and Fetal Alcohol Syndrome

Description, Diagnosis, and Prevention

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Abstract

Alcohol abuse is associated with an increased risk of cancer and birth defects, two disease processes that at some stage involve alterations in gene expression and cell development. The biochemical, molecular, and physiological mechanisms through which alcohol consumption produces these pathological effects are not thoroughly understood and seem to be multifactorial in nature. This chapter focuses largely on the experimental systems that have provided insights into potential mechanisms underlying the carcinogenic and teratogenic effects of alcohol abuse. The epidemiologic studies that established the association between alcohol abuse and cancer and birth defects have recently been reviewed (Garro and Lieber, 1990; Abel and Sokol, 1989) and are not discussed in detail here.

Keywords

  • Ethanol Consumption
  • Ethanol Exposure
  • Chronic Ethanol
  • Fetal Alcohol Syndrome
  • Prenatal Alcohol Exposure

These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Garro, A.J., Gordon, B.H.J., Lieber, C.S. (1992). Alcohol Abuse: Carcinogenic Effects and Fetal Alcohol Syndrome. In: Medical and Nutritional Complications of Alcoholism. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3320-7_15

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