The Role of Retinoic Acid and Cellular Retinoic Acid-Binding Protein in the Regenerating Amphibian Limb

  • Malcolm Maden
  • Nick Waterson
  • Dennis Summerbell
  • Jean Maignon
  • Michel Darmon
  • Braham Shroot
Part of the NATO ASI Series book series (NSSA, volume 205)


We describe here two aspects of our work on retinoic acid (RA) and pattern formation in the regenerating limb. The first concerns the presence of endogenous RA in the regenerating limb and the second concerns experiments on the role of cellular retinoic acid-binding protein (CRABP) in the process of pattern respecification.


Retinoic Acid Retinyl Palmitate Synthetic Retinoid Naphthoic Acid Cone Stage 
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Copyright information

© Springer Science+Business Media New York 1991

Authors and Affiliations

  • Malcolm Maden
    • 1
  • Nick Waterson
    • 2
  • Dennis Summerbell
    • 2
  • Jean Maignon
    • 3
  • Michel Darmon
    • 4
  • Braham Shroot
    • 4
  1. 1.Anatomy & Human Biology GroupKings CollegeLondonUK
  2. 2.Division of Physical Biochemistry National Institute for Medical ResearchLondonUK
  3. 3.Laboratoires de Recherche L’OrealAulnaySous-BoisFrance
  4. 4.Centre International de Recherches Dermatologiques GaldermaSophia AntipolisValbonneFrance

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