Comparative Metabolism and Genotoxicity Data on Benzene: Their Role in Cancer Risk Assessment

  • Sandro Grilli
  • Silvio Parodi
  • Maurizio Taningher
  • Annamaria Colacci
Part of the NATO ASI Series book series (NSSA, volume 232)

Abstract

Benzene is one of the chemicals with the largest production and utilization, with widest environmental spread and availability of animal and human toxicology data (IA-RC, 1982a). It is, therefore, a model compound which requires metabolic activation in order to exert toxic effects.

Keywords

Phenol Leukemia Toluene Polycyclic Aromatic Hydrocarbon Pyrene 

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Copyright information

© Springer Science+Business Media New York 1992

Authors and Affiliations

  • Sandro Grilli
    • 2
  • Silvio Parodi
    • 1
    • 3
  • Maurizio Taningher
    • 1
    • 3
  • Annamaria Colacci
    • 1
    • 4
  1. 1.Centro Interuniversitario per la Ricerca sul CancroItaly
  2. 2.Istituto di CancerologiaBolognaItaly
  3. 3.Istituto Nazionale per la Ricerca sul Cancro (IST)GenovaItaly
  4. 4.IST-Biotechnology Satellite Unit-BolognaBolognaItaly

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