Abstract
Widespread use of insecticides has led to the selection of resistance in many insect species. The biochemical mechanisms responsible are of two broad classes: enhanced insecticide degradation by various enzyme groups, and decreased sensitivity of the target protein to the toxicant.1 As the target for organophosphorus (OP) and carbamate insecticides, acetylcholinesterase (AChE) forms showing insensitivity to these inhibitors have been selected in various pests.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
F.J. Oppenoorth. Comprehensive Insect Physiology Biochemistry and Pharmacology, Vol. 12, ed. G.A. Kerkut & L.I. Gilbert. Pergamon, Oxford, 713–773 (1985).
G.D. Moores, A.L. Devonshire and I. Denholm. Bull. Ent. Res. 78:537 (1988).
S.J. Gould, S. Subramani and I.E. Scheffler. Proc. Natl. Acad. Sci. USA 86:1934 (1989).
L.M.C. Hall and C.A. Malcolm. Cell Mol. Neurobiol. 11:131 (1991).
L.M.C. Hall and P. Spierer. EMBO J. 5:2949 (1986).
D. Fournier, F. Karch, J.M. Bride, L.M.C. Hall, J.B. Berge and P. Spierer. J. Mol. Biol. 210:15 (1989).
J.L. Sussman, M. Hard, F. Frolow, C. Oefner, A. Goldman, L. Toker and I. Silman. Science 253:872 (1991).
D. Fournier, J.M. Bride, F. Karch and J.B. Berge. FEBS Lett. 238:333 (1988).
R. Haas, T.L. Marshall and T.L. Rosenberry. Biochemistry 27:6453 (1988).
R.W. Steele and B.N. Smallman. Biochim. Biophys. Acta. 445:147 (1976).
D. Fournier, J.B. Berge, M.L. Cardoso de Almeida and C. Bordier. J. Neurochem. 50:1158 (1988).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1992 Springer Science+Business Media New York
About this chapter
Cite this chapter
Williamson, M.S., Moores, G.D., Devonshire, A.L. (1992). Altered Forms of Acetylcholinesterase in Insecticide-Resistant Houseflies (Musca Domestica) . In: Shafferman, A., Velan, B. (eds) Multidisciplinary Approaches to Cholinesterase Functions. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3046-6_11
Download citation
DOI: https://doi.org/10.1007/978-1-4615-3046-6_11
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-6328-6
Online ISBN: 978-1-4615-3046-6
eBook Packages: Springer Book Archive