Altered Forms of Acetylcholinesterase in Insecticide-Resistant Houseflies (Musca Domestica)

  • Martin S. Williamson
  • Graham D. Moores
  • Alan L. Devonshire


Widespread use of insecticides has led to the selection of resistance in many insect species. The biochemical mechanisms responsible are of two broad classes: enhanced insecticide degradation by various enzyme groups, and decreased sensitivity of the target protein to the toxicant.1 As the target for organophosphorus (OP) and carbamate insecticides, acetylcholinesterase (AChE) forms showing insensitivity to these inhibitors have been selected in various pests.


Carbamate Insecticide Altered Form Degenerate Oligonucleotide Primer United Kingdom Introduction AChE Gene 
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Copyright information

© Springer Science+Business Media New York 1992

Authors and Affiliations

  • Martin S. Williamson
    • 1
  • Graham D. Moores
    • 1
  • Alan L. Devonshire
    • 1
  1. 1.Institute of Arable Crops Research Rothamsted Experimental Station HarpendenAFRCHertsUK

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