Fibronectin-Binding Proteins of Staphylococci and Streptococci

  • Hans-Peter Müller
  • Martin Lindberg
Part of the Federation of European Microbiological Societies Symposium Series book series (FEMS, volume 61)


Fibronectin (Fn) is a large dimeric glycoprotein found in soluble form in plasma and other body fluids and in fibrillar form in the extracellular matrix of connective tissue. The protein contains a number of domains capable of independent binding to different ligands (Figure 1). The eukaryotic cell-binding site within Fn containing an RGD sequence interacts with a specific receptor of the integrin family.1,2 It has also been shown that the C-terminal heparin-binding domain can promote eucaryotic cell adhesion by an RGD-independent mechanism.3


Synthetic Peptide Repeat Unit Acidic Amino Acid Fibronectin Receptor Fibronectin Binding 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1992

Authors and Affiliations

  • Hans-Peter Müller
    • 1
  • Martin Lindberg
    • 1
  1. 1.Department of MicrobiologySwedish University of Agricultural SciencesUppsalaSweden

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