Abstract
The arenaviruses are primarily viruses of rodents, although a minority of them cause serious disease in humans. They were originally grouped together on the basis of their appearance in the electron microscope (Dalton et al.,1968; Murphy and Whitfield, 1975) and serological cross-reactivity in complement fixation and immunofluorescence tests (Rowe et al.,1970; Casals et al., 1975; Wulff et al., 1978). The production and use of monoclonal antibodies have reinforced and refined our ability to group these viruses and to recognize variation among strains of the same virus (Buchmeier et al., 1981; Howard et al., 1985; Sanchez et al., 1989; Ruo et al., 1991) Analysis of the structural components of several members of the family has confirmed their general similarity at the molecular level (see Bishop and Auperin, 1987; Buchmeier and Parekh, 1987, for reviews) and has provided, through nucleotide sequencing, a means by which we can begin to make quantitative estimates of the relationships among these viruses. Here I have collected together a directory of the arenavirus sequence data currently available in widely distributed databases, multiple alignments of nucleocapsid (N) and glycoprotein precursor (GPC) protein amino acid sequences, and present phylogenetic trees based on these sequences, which graphically summarize the relationships among these viruses.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Auperin, D. D., and McCormick, J. B., 1988, Nucleotide sequence of the Lassa Virus (Josiah strain) S genome RNA and amino acid sequence comparison of the N and GPC proteins to other arenaviruses, Virology 168:421.
Auperin, D., Dimock, K., Cash, P., Rawls, W. E., Leung, W. C., and Bishop, D. H. L., 1982a, Analyses of the genomes of prototype Pichinde arenavirus and a virulent derivative of Pichinde Munchique: Evidence for sequence conservation at the 3’-termini of their viral RNA species, Virology 116:363.
Auperin, D. D., Compans, R. W., and Bishop, D. H. L., 1982b, Nucleotide sequence conservation at the 3’ termini of the viron RNA species of New World and Old World arenaviruses, Virology 121:200.
Auperin, D. D., Romanowski, V., Galinski, M., and Bishop, D. H. L., 1984, Sequencing studies of Pichinde arenavirus S RNA indicate a novel coding strategy, an ambisense viral S RNA, J. Virol. 52:897.
Auperin, D. D., Sasso, D. R., and McCormick, J. B., 1986, Nucleotide sequence of the glycoprotein gene and intergenic region of the Lassa virus S genome RNA, Virology 154:155.
Bishop, D. H. L., and Auperin, D. D., 1987, Arenavirus gene structure and organization, Curr. Top. Microbiol. Immunol. 13:5.
Buchmeier, M. J., and Parekh, B. S., 1987, Protein structure and expression among arena-viruses, Curr. Top. Microbiol. Immunol. 133:41.
Buchmeier, M. J., Lewicki, H. A., Tomori, O., and Oldstone, M. B. A., 1981, Monoclonal antibodies to lymphocytic choriomeningitis and Pichinde viruses: Generation, characterization and cross-reactivity with other arenaviruses, Virology 113:73.
Burns, J. W., Salvato, M. S., and Buchmeier, M. J., 1990, Molecular architecture of lymphocytic choriomeningitis virus, in: Proc. VIllth Int. Cong. Virol., International Union of Microbiological Societies, Berlin, Abstr. W3–001.
Casals, J., Buckley, S. M., and Cedeno, R., 1975, Antigenic properties of the arenaviruses, Bull. WHO 52:421.
Clegg, J. C. S., and Oram, J. D., 1985, Molecular cloning of Lassa virus RNA: Nucleotide sequence and expression of the nucleocapsid protein gene, Virology 144:363.
Clegg, J. C. S., Wilson, S. M., and Oram, J. D., 1990, Nucleotide sequence of the S RNA of Lassa virus (Nigerian strain) and comparative analysis of arenavirus gene products, Virus Res. 18:151.
Dalton, A. J., Rowe, W. P., Smith, G. H., Wilsnack, R. E., and Pugh, W. E., 1968, Morphological and cytochemical studies on lymphocytic choriomeningitis virus, J. Virol. 2:1465.
Felsenstein, J., 1985, Confidence limits on phylogenies: an approach using the bootstrap, Evolution 39:783.
Feng, D-F., and Doolittle, R. F., 1987, Progressive sequence alignment as a prerequisite to correct phylogenetic trees, J. Mol. Evol. 25:351.
Feng, D-F., Doolittle, R. F., 1990, Progressive alignment and phylogenetic tree construction of protein sequences, Meth. Enzymol. 183:375.
Franze-Fernandez, M. T., Zetina, C., Iapalucci, S., Lucero, M. A., Bouissou, C., Lopez, R., Rey, O., Daheli, M., Cohen, G. N., and Zakin, M. M., 1987, Molecular structure and early events in the replication of Tacaribe arenavirus S RNA, Virus Res. 7:309.
Ghiringhelli, P. D., Rivera Pomar, R. V., Baro, N. I., Rosas, M. F., Grau, O., and Romanowski, V., 1989, Nucleocapsid protein gene of Junin arenavirus (cDNA sequence), Nucleic Acids Res. 17:8001.
Ghiringhelli, P. D., Rivera-Pomar, R. V., Lozano, M. E., Grau, O., and Romanowski, V., 1991, Molecular organization of Junin virus S RNA: Complete nucleotide sequence, relationship with other members of the Arenaviridae and unusual secondary structures, J. Gen. Virol. 72:2129.
Griffiths, C. M., Wilson, S. M., and Clegg, J. C. S., 1992, Sequence of the nucleocapsid protein gene of Machupo virus: close relationship with another South American pathogenic arenavirus, Junin, Arch. Virol. 124:371.
Hahn, C. S., Lustig, S., Strauss, E. G., and Strauss, J. H., 1988, Western equine encephalitis virus is a recombinant virus, Proc. Natl. Acad. Sci. USA 85:5997.
Higgins, D. G., and Sharp, P. M., 1988, CLUSTAL: A package for performing multiple sequence alignments on a microcomputer, Gene 73:237.
Higgins, D. G., and Sharp, P. M., 1989, Fast and sensitive multiple sequence alignments on a microcomputer, Corn put. Appl. Biosci. 5:151.
Higgins, D. G., Bleasby, A. J., and Fuchs, R., 1992, CLUSTAL V: Improved software for multiple sequence alignment, Comput. Appl. Biosci. 8:189.
Howard, C. R., Lewicki, H., Allison, L., Salter, M., and Buchmeier, M. J., 1985, Properties and characterization of monoclonal antibodies to Tacaribe virus, J. Gen. Virol. 66:1383.
Iapalucci, S., Lopez, R., Rey, O., Lopez, N., Franze-Fernandez, M. T., Cohen, G. N., Lucero, M., Ochoa, A., and Zakin, M. M., 1989a, Tacaribe virus L gene encodes a protein of 2210 amino acid residues, Virology 170:40.
Iapalucci, S., Lopez, N., Rey, O., Zakin, M. M., Cohen, G. N., and Franze-Fernandez, M. T., 1989b, The 5’ region of Tacaribe virus L RNA encodes a protein with a potential metal binding domain, Virology 173:357.
Iapalucci, S., Lopez, N., and Franze-Fernandez, M. T., 1991, The 3’ end termini of the Tacaribe virus sub-genomic RNAs, Virology 182:269.
Kimura, M., 1983, The Neutral Theory of Molecular Evolution, Cambridge University Press, Cambridge.
Levinson, R. S., Strauss, J. H., and Strauss, E. G., 1990, Complete sequence of the genomic RNA of O’Nyong-nyong virus and its use in the construction of alphavirus phylogenetic trees, Virology 175:110.
Maiztegui, J. I., Barrera Oro, J. G., Feuillade, M. R., Peters, C. J., Vallejos, D., and McKee, K. T., 1990, Inoculation of human volunteers with Candid 1, a live attenuated Junin virus vaccine candidate, in: Proc. VIllth Int. Cong. Virol., International Union of Microbiological Societies, Berlin, Abstr. W70–005.
Murphy, F. A., and Whitfield, S. G., 1975, Morphology and morphogenesis of arenaviruses, Bull. WHO 52:479.
Peters, C. J., Jahrling, P. B., Liu, C. T., Kenyon, R. H., McKee, K. T., and Barrera Oro, J. G., 1987, Experimental studies of arenaviral hemorrhagic fevers, Curr. Top. Microbiol. Immunol. 134:5.
Romanowski, V., and Bishop, D. H. L., 1985, Conserved sequences and coding of two strains of lymphocytic choriomeningitis virus (WE and ARM) and Pichinde arena-virus, Virus. Res. 2:35.
Romanowski, V., Matsuura, Y., and Bishop, D. H. L., 1985, Complete sequence of the S RNA of lymphocytic choriomeningitis virus (WE strain) compared to that of Pichinde arenavirus, Virus Res. 3:101.
Rowe, W. P., Pugh, W. E., Webb, P. A., and Peters, C. J., 1970, Serological relationship of the Tacaribe complex of viruses to lymphocytic choriomeningitis virus, J. Virol. 5:289.
Ruo, S. L., Mitchell, S. W., Kiley, M. P., Roumillat, L. F., Fisher-Hoch, S. P., and McCormick, J. B., 1991, Antigenic relatedness between arenaviruses defined at the epitope level by monoclonal antibodies, J. Gen. Virol. 72:549.
Saitou, N., and Nei, M., 1987, The neighbor-joining method: a new method for reconstructing phylogenetic trees, Mol. Biol. Evol. 4:406.
Salvato, M., and Shimomaye, E. M., 1989, The completed sequence of lymphocytic choriomeningitis virus reveals a unique RNA structure and a gene for a zinc-finger protein, Virology 173:1.
Salvato, M., Shimomaye, E., Southern, P., and Oldstone, M. B. A., 1988, Virus-lymphocyte interactions. IV. Molecular characterization of LCMV Armstrong (CTL+) small genomic segment and that of its variant, clone 13 (CTL-), Virology 164:517.
Salvato, M. S., Shimomaye, E. M., and Oldstone, M. B. A., 1989, The primary structure of the lymphocytic choriomeningitis virus L gene encodes a putative RNA polymerase, Virology 169:377.
Sanchez, A., Pifat, D. Y., Kenyon, R. H., Peters, C. J., McCormick, J. B., and Kiley, M. P., 1989, Junin virus monoclonal antibodies: characterization and cross-reaction with other viruses, J. Gen. Virol. 70:1125.
Singh, M. K., Fuller-Pace, F. V., Buchmeier, M. J., and Southern, P. J., 1987, Analysis of the genomic L RNA segment from lymphocytic choriomeningitis virus, Virology 161:448.
Swofford, D. L., and Olsen, G. J., 1990, Phylogeny reconstruction, in: Phylogeny Recon- struction (D. M. Hillis and C. Moritz, eds.), Sinauer Associates, Sunderland, MA.
Weissenbacher, M. C., Coto, C. E., and Calello, M. A., 1976, Cross-protection between Tacaribe complex viruses: Presence of neutralizing antibodies against Junin virus (Argentine hemorrhagic fever) in guinea pigs infected with Tacaribe virus, Intervirology 6:42.
Weissenbacher, M. C., Laguens, R. P., and Coto, C. E., 1987, Argentine hemorrhagic fever, Curr. Top. Microbiol. Immunol. 134:79.
Wilson, S. M., Clegg, J. C. S., and Oram, J. D., 1991, Sequence analysis of the S RNA of the African arenavirus Mopeia: An unusual secondary structure feature in the intergenic region, Virology 180:543.
Wulff, H., Lange, J. V., and Webb, P., 1978, Interrelationship among arenaviruses measured by immunofluorescence, Intervirology 9:344.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1993 Springer Science+Business Media New York
About this chapter
Cite this chapter
Clegg, J.C.S. (1993). Molecular Phylogeny of the Arenaviruses and Guide to Published Sequence Data. In: Salvato, M.S. (eds) The Arenaviridae. The Viruses. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3028-2_10
Download citation
DOI: https://doi.org/10.1007/978-1-4615-3028-2_10
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-6320-0
Online ISBN: 978-1-4615-3028-2
eBook Packages: Springer Book Archive