Abstract
Aristeromycin (1) (Figure 1) is a carbocyclic analogue of adenosine which was first synthesized in racemic form in 1966.1 Shortly thereafter, the compound was isolated from the fermentation broth of Streptomyces citricolor, its structure was elucidated, and its absolute configuration was determined.2 Aristeromycin displays a variety of interesting biological activities,3,4 including inhibition of cell division and elongation in rice plants, inhibition of AMP synthesis in mammalian cells, and inhibition of the enzyme S-adenosylhomocysteine hydrolase.5
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Parry, R.J. (1992). Investigations of the Biosynthesis of Aristeromycin. In: Petroski, R.J., McCormick, S.P. (eds) Secondary-Metabolite Biosynthesis and Metabolism. Environmental Science Research, vol 44. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3012-1_7
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DOI: https://doi.org/10.1007/978-1-4615-3012-1_7
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