Formation, Inhibition of Formation, and Repair of Oxidative 8-Hydroxyguanine DNA Damage
Oxygen radicals are produced by many carcinogenic agents and by ionizing radiation, and cause DNA damage in vitro and in vivo. Oxygen radicals are also produced in vivo during cellular metabolism of oxygen. Therefore, studies on DNA damage induced by oxygen radicals should be helpful in elucidating the mechanisms of induction of cancer by ionizing radiation and environmental chemicals as well as spontaneous carcinogenesis during aging.
KeywordsHigh Performance Liquid Chromatography Oxygen Radical Nickel Compound Cigarette Smoke Condensate Potassium Bromate
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