Abstract
It is well known that the rat and rabbit carotid body (CB) contains more dopamine (DA) than norepinephrine (NE) (Hellström and Koslow, 1975; Hansen and Christie, 1981; Mir et al., 1982; Leitner et al., 1986) and it has been supposed for a long time that the storage sites for DA and NE are the glomus cells and the postganglionnic sympathetic innervation, respectively. However, biochemical results have shown that sympathectomy does not induce a total disappearance of the CB NE content in the rabbit (Fidone and Gonzalez, 1982; Leitner et al., 1986) as well as in the rat (Pequignot et al., 1986). These results suggest that part of the CB NE is probably stored in the glomus cells. However, several possibilities must be considered: are there different kinds of glomus cells (i.e. dopaminergic/noradrenergic) or do each glomus cell contains a mixture of DA and NE? If so, is the DA/NE ratio variable from cell to cell or is it the same for all cells?
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© 1993 Springer Science+Business Media New York
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Verna, A., Schamel, A., Pequignot, JM. (1993). Noradrenergic Glomus Cells in the Carotid Body: An Autoradiographic and Immunocytochemical Study in the Rabbit and Rat. In: Data, P.G., Acker, H., Lahiri, S. (eds) Neurobiology and Cell Physiology of Chemoreception. Advances in Experimental Medicine and Biology, vol 337. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2966-8_14
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DOI: https://doi.org/10.1007/978-1-4615-2966-8_14
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