Abstract
Purified polymorphonuclear leukocytes (PMN), obtained from blood of healthy, non-allergic donors were exposed to organic dust extracts of airborne particulated matter. The dust was collected on glass fibre filter sheets using high volume samplers HVS 150 during the winter season 1989/90 in a highly industrialized region of northwestern Germany. The PMN were incubated either with the organic dust extracts alone or subsequently stimulated with either Ca-Ionophore A23187 or with opsonized zymosan.IL-8 release was measured in the supernatants using an ELISA technique with a monoclonal antibody against IL-8.
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© 1993 Springer Science+Business Media New York
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Hitzfeld, B., Friedrichs, K.H., Behrendt, H. (1993). Interleukin 8 Release From Human Pmn Is Modified By Airborne Particulated Matter. In: Lindley, I.J.D., Westwick, J., Kunkel, S. (eds) The Chemokines. Advances in Experimental Medicine and Biology, vol 351. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2952-1_34
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DOI: https://doi.org/10.1007/978-1-4615-2952-1_34
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-6283-8
Online ISBN: 978-1-4615-2952-1
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