Advertisement

The Chemokines pp 183-186 | Cite as

Overview of Chemokines

  • Joost J. Oppenheim
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 351)

Abstract

It has been very difficult for investigators involved in studies of the chemotactic factors to agree on terminology; hence the plethora of strange names for these cytokines. It was therefore especially gratifying that this intensely involved and partisan group of researchers could meet and after heated discussion reach an almost unanimous agreement to endorse the chemokine α and β nomenclature for the subfamilies of chemoattractant cytokines whose genes are located on human chromosome 4q and 17q regions respectively.

Keywords

Chemotactic Activity Chemotaxis Assay Basophil Histamine Release Chemoattractant Cytokine Sweat Gland Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Schall, T.J., K. Bacon, K.I. Toy, and D.V. Goedell. 1990. Selective attraction of monocytes and T lymphocytes of the memory phenotype by the cytokine RANTES. Nature34: 669.CrossRefGoogle Scholar
  2. 2.
    Broxmeyer, H.E., B. Sherry, L. Lu, S. Cooper, K.O. Oh, P. Tekamp-Olson, B.S. Kwon, and A. Cerami. 1990. Enhancing and suppressing effects of recombinant murine macrophage inflammatory proteins on colony formation in vitroby bone marrow myeloid progenitor cells. Blood76: 110.Google Scholar
  3. 3.
    Richmond, A., E. Balentien, H.G. Thomas, G. Flaggs, D.E. Barton, J. Spiess, R. Bordoni, U. Francke, and R. Derynck. 1988. Molecular characterization and chromosomal mapping of melanoma growth stimulatory activity, a growth factor structurally related to 13-thromboglobulin. EMBO J. 7: 2025.PubMedGoogle Scholar
  4. 4.
    Krueger, G., C. Jorgensen, C. Miller, J. Schroeder, M. Sticherling, and E. Christophers. 1990. Effects of IL-8 on epidermal proliferation. J. Invest.Dermatol.94: 545 (Abstract).CrossRefGoogle Scholar
  5. 5.
    Senior, R.M., G.L. Griffin, J.S. Juang, D.A. Walz, and T.F. Deuel. 1983. Chemotactic activity of a platelet alpha protein for fibroblasts. J.Cell.Biol.96: 382.PubMedCrossRefGoogle Scholar
  6. 6.
    Castor, C.W., J.W. Miller, and D.A. Walz. 1983. Structural and biological characteristics of connective tissue activating peptide (CTAP-3), a major human platelet-derived growth factor. Proc.Natl.Acad.Sci. USA80: 765.PubMedCrossRefGoogle Scholar
  7. 7.
    Fahey, T.J. III., K.J. Tracey, P. Tekamp-Olsen, L.S. Cousens, W.G. Jones, T. Shires, A. Cerami, and B. Sherry. 1992. Macrophage inflammatory protein 1 modulates macrophage function. J.Immunol.148: 2764.PubMedGoogle Scholar
  8. 8.
    Oppenheim, J.J., C.O.C. Zachariae, N. Mukaida, and K. Matsushima. 1991. Properties of the novel proinflammatory supergene “intercrine” cytokine family. Ann.Rev.Immunol.9: 617.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • Joost J. Oppenheim
    • 1
  1. 1.Laboratory of Molecular ImmunoregulationNational Cancer InstituteFrederickUSA

Personalised recommendations