The Multiple Accessory Cell Concept: Its Relevance to the Development of Adjuvants and Vaccines

  • Nico Van Rooijen
Part of the NATO ASI Series book series (NSSA, volume 261)


When studying the mechanism of immunoadjuvant activity, it is important to realize that various non-lymphoid accessory cells are required for the induction of the antibody response and for the generation of immunological memory. These cells have a crucial function in the processing and/or presentation of antigens to lymphoid cells. For that reason, they have to be considered one of the most obvious targets in the development of adjuvants and vaccines.


Dendritic Cell Marginal Zone Lymphoid Follicle Accessory Cell Follicular Dendritic Cell 
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Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • Nico Van Rooijen
    • 1
  1. 1.Dept. of Cell Biology, Faculty of MedicineVrije UniversiteitAmsterdamThe Netherlands

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