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Theoretical Analysis of Coronary Blood Flow and Tissue Oxygen Pressure-Control

  • Jos A. E. Spaan
  • Jenny Dankelman
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 346)

Abstract

Coronary blood flow is tightly coupled to the myocardial oxygen consumption. We have presented a control model based on the assumption that the tissue oxygen pressure is the controlled variable. The coronary blood flow in itself is not a controlled variable but merely the result of a different control system: the tissue oxygen pressure. From our control equation there is no relation between the slope of the autoregulation curve and the gain of the tissue P02 control system. The slope is independent of the level of oxygen consumption.

Keywords

Coronary Blood Flow Myocardial Oxygen Consumption Open Loop Gain Tissue Oxygen Pressure Autoregulation Curve 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • Jos A. E. Spaan
    • 1
    • 2
  • Jenny Dankelman
    • 2
  1. 1.Department of Medical Physics and InformaticsUniversity of Amsterdam AMCAmsterdamThe Netherlands
  2. 2.Laboratory for Measurement and ControlDelft University of TechnologyDelftThe Netherlands

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