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Neuropharmacological and Neurophysiological Dissection of Inhibition in the Mammalian Dorsal Cochlear Nucleus

  • Edward F. Evans
  • Wei Zhao
Chapter
Part of the NATO ASI series book series (NSSA, volume 239)

Abstract

The cochlear nucleus (CN) is the first stage in the auditory pathway at which inhibition (mediated synaptically in response to single stimuli), is encountered, as was first shown by Galambos (’44) — in recordings probably from outlying cells of the dorsal cochlear nucleus (Galambos and Davis,’ 48).

Keywords

Receptive Field Cochlear Nucleus Hand Panel Dorsal Cochlear Nucleus Iontophoretic Application 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Cant, N. B. and Gaston, K. C., 1982, Pathways connecting the right and left cochlear nuclei. J.Comp.Neurol., 212: 313–326.PubMedCrossRefGoogle Scholar
  2. Caspary, D. M., Havey, D. C. and Faingold, C. L., 1979, Effects of microiontophoretically applied glycine and GABA on neuronal response patterns in the cochlear nuclei, Brain Res., 172: 179–185.PubMedCrossRefGoogle Scholar
  3. Caspary, D. M., Rybak, L. P. and Faingold, C. L., 1984, Baclofen reduces tone-evoked activity of cochlear nucleus neurons, Hear.Res., 13: 113–122.PubMedCrossRefGoogle Scholar
  4. Caspary, D. M., Pazara, K. E., Kossl, M. and Faingold, C. L., 1987, Strychnine alters the fusiform cell output from the dorsal cochlear nucleus, Brain Res., 417: 273–282.PubMedCrossRefGoogle Scholar
  5. Evans, E. F., 1974, Auditory frequency selectivity and the cochlear nerve, in: “Facts and Models in Hearing”, E. Zwicker and E. Terhardt, eds., Springer-Verlag, Heidelberg, 118–129.CrossRefGoogle Scholar
  6. Evans, E. F., 1979a, Neuroleptanaesthesia for the guinea pig: an ideal anaesthetic procedure for long-term physiological studies of the cochlea, Arch. Otolaryngol., 105: 185–186.PubMedCrossRefGoogle Scholar
  7. Evans, E. F., 1979b, Single unit studies of the mammalian auditory nerve, in: “Auditory Investigations: The Scientific and Technological Basis”, H.A. Beagley, ed., Oxford University Press, Oxford, 324–367.Google Scholar
  8. Evans, E. F., 1985, Aspects of the neuronal coding of time in the mammalian peripheral auditory system relevant to temporal resolution, in: “Time Resolution in Auditory Systems: 11th Danavox Symposium”, A. Michelsen, ed., Springer Verlag, Berlin Heidelberg New York, 74–95.CrossRefGoogle Scholar
  9. Evans, E. F. and Nelson, P. G., 1973a, The responses of single neurones in the cochlear nucleus of the cat as a function of their location and the anaesthetic state, Exp. Brain Res., 17: 402–427.PubMedGoogle Scholar
  10. Evans, E. F. and Nelson, P. G., 1973b, On the functional relationship between the dorsal and ventral divisions of the cochlear nucleus of the cat, Exp. Brain Res., 17: 428–442.PubMedGoogle Scholar
  11. Evans, E. F., Pratt, S. R., Spenner, H. and Cooper, N. P., 1991, Comparisons of physiological and behavioural properties: auditory frequency selectivity, in: “9th International Symposium on Hearing: Auditory Physiology and Perception”, Y. Cazals, ed., Pergamon Press Oxford, 1–6.Google Scholar
  12. Evans, E. F. and Zhao, W., 1992, Inhibition in the dorsal cochlear nucleus: pharmacological dissection, varieties, nature and possible functions, in: “Cochlear Nucleus: Structure and Function in Relation to Modelling”, Vol. 3 of Advances in Speech Hearing and Language Processing, W.A. Ainsworth, ed., (In Press).Google Scholar
  13. Galambos, R., 1944, Inhibition of activity in single auditory nerve fibers by acoustic stimulation. J. Neurophysiol., 7: 287–303.Google Scholar
  14. Galambos, R. and Davis, H., 1948, Action potentials from single auditory nerve fibers?, Science, 108:513–513.PubMedCrossRefGoogle Scholar
  15. Hackney, C. M., Osen, K. K. and Kolston, J., 1990, Anatomy of the cochlear nuclear complex of guinea pig, Anat. Embryol., 182:123–149.PubMedCrossRefGoogle Scholar
  16. Klinke, R., Boerger, G. and Gruber, J., 1970, The influence of the frequency relation in dichotic stimulation upon the cochlear nucleus activity, in: “Frequency Analysis and Periodicity Detection in Hearing”, Plomp R and Smoorenburg GF, eds., Sijthoff Leiden, 162-167.Google Scholar
  17. Mast, T. E., 1970, Binaural interaction and contralateral inhibition in dorsal cochlear nucleus of the chinchilla, J. Neurophysiol., 33:108–115.PubMedGoogle Scholar
  18. Osen, K. K., Ottersen, O. P. and Storm-Mathisen, J., 1990, Colocalization of glycine-like and GABA-like immunoreactivities: a semiquantitative study of individual neurons in the dorsal cochlear nucleus of cat, in: “Glycine Transmission”, P. Ottersen and J. Storm-Mathisen, eds. 417-451.Google Scholar
  19. Palmer, A. R. and Evans, E. F., 1982, Intensity coding in the auditory periphery of the cat: Responses of cochlear nerve and cochlear nucleus neurons to signals in the presence of Bandstop masking noise, Hearing. Res., 7:305–323.CrossRefGoogle Scholar
  20. Wenthold, R. J., 1987, Evidence for a glycinergic pathway connecting the two cochlear nuclei: an immunocytochemical and retrograde transport study, Brain. Res., 415:183–187.PubMedCrossRefGoogle Scholar
  21. Young, E. C., 1985, Response Characteristics of Neurons of the Cochlear Nuclei, in: “Hearing Science”, Berlin, C. I., Ed., San Diego, College-Hill Press, 423–460.Google Scholar
  22. Young, E. D., Shomer, W. P., White, J. A., Robert, J. M. and Voigt, H. F., 1988, Response Properties of Cochlear Nucleus Neurones in Relationship to Physiological Mechanisms, Annual Symposium of The Neurosciences Institute, Wiley and Sons, 277-312.Google Scholar
  23. Zhao, W. and Evans, E. F., 1990, Pharmacological microiontophoretic investigation of receptive-field and temporal properties of units in the cochlear nucleus, British Journal of Audiology, 24: 193–193.Google Scholar
  24. Zhao, W. and Evans, E. F., 1991, Dorsal cochlear nucleus units: neuropharmacological effects on dynamic range and off-inhibition, British Journal of Audiology, 25:53–54.Google Scholar
  25. Zhao, W. and Evans, E. F., 1992, Bandwidths of excitatory and inhibitory receptive fields in the dorsal cochlear nucleus, British Journal of Audiology, 26-179–180.Google Scholar

Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • Edward F. Evans
    • 1
  • Wei Zhao
    • 1
  1. 1.Department of Communication and NeuroscienceKeele UniversityKeele, StaffsUK

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