Follicular Dendritic Cells Do Not Produce TNF-α Nor its Receptor

  • Isabelle Maneini
  • Alain Bosseloir
  • Elisabeth Hooghe-Peters
  • Ernst Heinen
  • Léon Simar
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 329)


The immunomodulatory role of TNF-α on the humoral response is complex: in vitro, TNF-α can enhance the proliferation of activated B lymphocytes and, in certain conditions, the Ig production. In vivo, it probably acts on the differenciation and growth of B lymphocytes (Kehrl el al., 1987).


Germinal Center Follicular Dendritic Cell Pokeweed Mitogen Lymph Follicle Peanut Agglutinin 
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Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • Isabelle Maneini
  • Alain Bosseloir
  • Elisabeth Hooghe-Peters
    • 2
  • Ernst Heinen
    • 1
  • Léon Simar
    • 1
  1. 1.Institute of Human Histology, University of Liège, and Department of PharmacologyBelgium
  2. 2.Medical School, Free University of BrusselsBelgium

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