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Follicular Dendritic Cells in Malignant Lymphomas - Distribution, Phenotypes & Ultrastructures

  • Kunihiko Maeda
  • Mikio Matsuda
  • Masaru Narabayashi
  • Ryuichi Nagashia
  • Noriyuki Degawa
  • Yutaka Imai
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 329)

Abstract

Follicular dendritic cells (FDC) are morphologically and functionally specialized cells which located within the reactive follicles of secondary lymphoid tissues. Recent years, several reports 1-9 described that FDCs also distributed in the lymphoid tissues involved with malignant lymphoma such as follicular lymphoma, diffuse lymphoma, and Hodgkinr’s disease. We expected that the comparison of the distribution pattern, morphology, immunological phenotypes and functional properties of FDC in malignant lymphoma with those of reactive tissues provide us important instances to understand the relationships between the functional properties or differentiation of FDC and the micro-environment organized by surrounding lymphoid cells. In the present study we had examined the morphology, surface phenotypes and distribution patterns of FDC in lymphoma including follicular lymphoma diffuse B-cell lymphoma and T-cell lymphoma and compared with those of reactive follicles.

Keywords

Follicular Lymphoma Malignant Lymphoma Follicular Dendritic Cell Secondary Lymphoid Tissue Immunological Phenotype 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • Kunihiko Maeda
    • 1
  • Mikio Matsuda
    • 1
  • Masaru Narabayashi
    • 1
  • Ryuichi Nagashia
    • 1
  • Noriyuki Degawa
    • 1
  • Yutaka Imai
    • 1
  1. 1.Department of PathologyYamagata University School of MedicineYamagataJapan

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