The Localization of Lymphokines in Murine Germinal Centers

  • T. Kasajima
  • A. Andoh
  • Y. Takeo
  • T. Nishikawa
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 329)


We have already reported that folliclar dendritic cells (FDCs) in the light zone of germinal centers (GCs) reacted positively for CD23, and that there is a close relationship between T cells and CD23-positive (CD23+) FDCs in the pattern of distribution on reactive and neoplastic follicles1. It was considered that CD23+ FDCs play an important role in interacting with T cells in follicles, and participate both in the formation of GCs and the preservation of folliclar structure.


Germinal Center Follicular Dendritic Cell Popliteal Lymph Node Primary Follicle Mantle Zone 
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Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • T. Kasajima
    • 1
  • A. Andoh
    • 1
  • Y. Takeo
    • 1
  • T. Nishikawa
    • 1
  1. 1.Department of PathologyTokyo Women’s Medical CollegeShinjuku-ku, TokyoJapan

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