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Comparison of Langerhans Cells and Interdigitating Reticulum Cells

  • Mikihiro Shamoto
  • Satoru Hosokawa
  • Masanori Shinzato
  • Chiyuki Kaneko
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 329)

Abstract

In our previous paper (1, 2) we reported that both OKT-6 and S-100 protein positive cells were observed in superficial and hilar lymph nodes. However, in mesenteric lymph nodes and spleens, only S-100 protein positive and OKT-6 negative cells were found. For immunostaining using OKT-6 and S-100 protein antibodies, mirror sections were used. Immunoelectron microscopy were also undertaken. We concluded that both positive cells were Langerhans cells (LCs), but only S-100 protein positive cells were interdigitating reticulum cells (IDCs). We then tried the double staining method in order to obtain more exact results, namely to prove whether LCs might be positive for both OKT-6 and S-100 protein.

Keywords

Mesenteric Lymph Node Hilar Lymph Node Methyl Benzoate Superficial Lymph Node Birbeck Granule 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • Mikihiro Shamoto
    • 1
  • Satoru Hosokawa
    • 1
  • Masanori Shinzato
    • 1
  • Chiyuki Kaneko
    • 1
  1. 1.Division of Pathological CytologyFujita Health University School of MedicineToyoake, AichiJapan

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