Abstract
Dendritic cells (DC) are very potent antigen presenting cells (1), that can be isolated from many lymphoid and non-lymphoid tissues from different species (2). Recently, we have demonstrated that in the peritoneal cavity of rats approximately 1 % of the cells are DC, based on similar morphological and functional characteristics as DC isolated from lymphoid organs (3). Next to this small number of DC, a large number of Mϕ (macrophages) is present in the peritoneal cavity, which are also capable of presenting antigen although to a lesser extent. Both cell types are bone marrow derived (4), but there are numerous morphological and functional differences (5) that suggest the existence of different cell lineages.
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© 1993 Plenum Press, New York
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van Vugt, E., Verdaasdonk, M.A.M., Kamperdijk, E.W.A., Beelen, R.H.J. (1993). Antigen Presenting Capacity of Peritoneal Macrophages and Dendritic Cells. In: Kamperdijk, E.W.A., Nieuwenhuis, P., Hoefsmit, E.C.M. (eds) Dendritic Cells in Fundamental and Clinical Immunology. Advances in Experimental Medicine and Biology, vol 329. Springer, New York, NY. https://doi.org/10.1007/978-1-4615-2930-9_22
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DOI: https://doi.org/10.1007/978-1-4615-2930-9_22
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