The Effect of Human Dendritic Cells on the Lectin-Induced Responsiveness of CD4+ T Cells To IL-2 and IL-4
Human peripheral blood dendritic cells (DC) are potent accessory cells (AC) for the lectin-induced proliferative response of T lymphocytes1. However, the contribution of DC to the responsiveness of lectin-induced T cells to IL-2 and IL-4 is not clearly understood. The AC-dependent induction of IL-2 responsiveness by mitogenic lectin has been reported2. It has been also shown that the proliferation of lectin-induced T cells is promoted bv IL-2 or IL-4 in the absence of AC.3
KeywordsArthritis Concanavalin Gentamycin
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