The Role of Alcohol and Aldehyde Dehydrogenases In Alcohol-Related Diseases: Clinical Studies of Molecular Markers
The rapid advances achieved in the field of molecular genetics over the past few years have had a profound effect on the study of complex conditions as well as single gene disorders. In the field of alcoholism and alcohol - related diseases, the application of these new techniques is now gathering pace. There is general agreement that a significant genetic component exists in alcoholism, as illustrated by the twin and adoption studies performed over the past 20 years, but this clearly does not conform to a simple Mendelian model. The central question that is being addressed concerns the inherited basis for the observed variation in individual responses to ethanol.
KeywordsHepatitis Aldehyde Adduct Carbonyl Stratification
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