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Plant Flavonoid Modulation of Immune and Inflammatory Cell Functions

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Nutrition and Immunology

Part of the book series: Human Nutrition ((HUNU))

Abstract

The immune system is a highly complex, intricately regulated group of cells whose integrated function is essential to health. Cells of the immune system may interact in a cognate cell-cell manner and may also respond to intercellular messages including hormones and cytokines elaborated by various cells. The immune system can be modified by diet, pharmacological agents, environmental pollutants, and naturally occurring food chemicals such as the flavonoids. Some effects of the flavonoids on the function of T cells, B cells, macrophages, NK cells, basophils, mast cells, neutrophils, eosinophils, and platelets will be described. Each of these cell types is involved in immunity and inflammation and the effects of the flavonoids on these cells will be considered in this broad context. This review is selective and does not cover the literature exhaustively.

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  1. Department of Medicine, Division of Allergy and Immunology, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, New York, 14203, USA

    Elliott Middleton Jr. & Chithan Kandaswami

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  1. Elliott Middleton Jr.
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  1. Wayne State University, Detroit, Michigan, USA

    David M. Klurfeld

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Middleton, E., Kandaswami, C. (1993). Plant Flavonoid Modulation of Immune and Inflammatory Cell Functions. In: Klurfeld, D.M. (eds) Nutrition and Immunology. Human Nutrition. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2900-2_12

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