Alexander, M., Newmark, H., and Miller, R. G., 1985, Oral beta carotene can increase the number of OKT4+ cells in human blood, Immunol. Lett. 9: 221–224.
CrossRef
CAS
Google Scholar
Anderson, R., and Theron, A. J., 1990, Physiological potential of ascorbate, beta-carotene and alpha-tocopherol individually and in combination in the prevention of tissue damage, carcinogenesis and immune dysfunction mediated by phagocyte-derived reactive oxidants, in: Aspects of Some Vitamins, Minerals and Enzymes in Health and Disease (G. H. Bourne, ed.), Karger, Basel, pp. 27–58.
Google Scholar
Anonymous, 1848, The vegetarian movement, Punch 15: 182.
Google Scholar
Bendich, A., ’1988}, Antioxidant vitamins and immune responses, in: Nutrition and Immunology (R. K. Chandra, ed.), Liss, New York, pp. 125–147.
Google Scholar
Bendich, A., 1989, Carotenoids and the immune response, J. Nutr. 119: 112–115.
CAS
Google Scholar
Bjelke, E., 1975, Dietary vitamin A and human lung cancer, Int. J. Cancer 15: 561–565.
CrossRef
CAS
Google Scholar
Bolognia, J., Murray, M., and Pawelek, J., 1989, UV-B-induced melanogenesis may be mediated through the MSH-receptor system, J. Invest. Dermatol. 92: 651–656.
CrossRef
CAS
Google Scholar
Burton, G. W., 1989, Antioxidant action of carotenoids, J. Nutr. 119: 109–111.
CAS
Google Scholar
Burton, G. W., and Ingold, K. U., 1984, Beta-carotene: An unusual type of lipid anti-oxidant, Science 224: 569–573.
CrossRef
CAS
Google Scholar
Clausen, S. W., 1931, Carotinemia and resistance to infections, Trans. Am. Pediatr. Soc. 43: 27–30.
Google Scholar
Colditz, G. A., Branch, L. G., Lipnick, R. J., Willett, W. C., Rosner, B., Posner, B. M., and Hennekens, D. H., 1985, Increased green and yellow vegetable intake and lowered cancer deaths in an elderly population, Am. J. Clin. Nutr. 41: 32–36.
CAS
Google Scholar
Cruz, P. D., Jr., Simon, J. C., Gerometta, J., Takashima, A., and Bergstreser, P. R., 1991, Effects of UVB radiation on antigen processing and presentation, 19th Annu. Meet. Soc. Photobiol. (Abstr.).
Google Scholar
Damianovich, S., and Pieri, C., 1991, Electroimmunology: Membrane potential, ion-channel activities, and stimulatory signal transduction in human T lymphocytes from young and elderly, Ann. N.Y. Acad. Sci. 621: 29–39.
CrossRef
Google Scholar
DeFabo, E. C., and Noonan, F. P., 1983, Mechanisms of immune suppression by ultraviolet light in vivo, J. Exp. Med. 157: 84–98.
CrossRef
Google Scholar
Fork, D. C., 1989, Photosynthesis, in: The Science of Photobiology, 2nd ed. (K. C. Smith, ed.), Plenum Press, New York, pp. 348–355.
Google Scholar
Fuller, C. J., Faulkner, H., Parker, R., and Roe, D. A., 1991, Effect of β-carotene on the photosuppression of cellular immune function in normal males, FASEB J. 5:A1323 (Abstr. 5528).
Google Scholar
Fuller, C. J., Faulker, H., Bendich, A., Parker, R. S., and Roe, D. A., 1992, Effect of β-carotene supplementation on photosuppression of delayed-type hypersensitivity in normal young men, Am. J. Clin. Nutr. 56: 654–690.
Google Scholar
Gensler, H. L., 1989, Reduction of immunosuppression in UV-irradiated mice by dietary retinyl palmitate plus canthaxanthin, Carcinogenesis 10: 203–207.
CrossRef
CAS
Google Scholar
Gilman-Sachs, A., Kim, Y. B., Pollard, M., and Snyder, D. L., 1991, Influence of aging, environmental antigens and dietary restriction on expression of lymphocyte subsets in germ-free and conventional Lobund-Wistar rats, J. Gerontol. 46:B101–B106.
CrossRef
CAS
Google Scholar
Goodman, D. S., and Huang, H. S., 1965, Biosynthesis of vitamin A with rat intestinal enzymes, Science 149: 879–880.
CrossRef
CAS
Google Scholar
Graham, S., 1983, Results of case-control studies of diet and cancer in Buffalo, New York, Cancer Res. 43:S2409–S2453.
Google Scholar
Granstein, R. D., 1990, Photoimmunology, in: Seminars in Dermatology, Vol. 9 (H. I. Maibach, ed.), Saunders, Philadelphia, pp. 16–24.
Google Scholar
Green, H. N., and Mellanby, E., 1930, Carotene and vitamin A: The anti-infective action of carotene, Br. J. Exp. Pathol 11: 81–89.
CAS
Google Scholar
Hadfield, G., and Garrod, L. F., 1947, Recent Advances in Pathology, 5th ed., Churchill, London, pp. 81–84.
Google Scholar
Hersey, P., Haran, G., Hasic, E., and Edwards, A., 1983, Alteration of T-cell subsets and induction of suppressor T-cell activity in normal subjects after exposure to sunlight, J. Immunol. 31: 171–174.
Google Scholar
Hersey, P., Noltorp, R., and Wilkinson, F. J., 1991, Effects of UV-A on natural killer (NK) cell activity, antigen presenting cells and induction of suppressor cells, 19th Annu. Meet. Am. Soc. Photobiol. (Abstr.).
Google Scholar
Holman, C. D. J., Armstrong, B. K., and Heenan, P. J., 1986, Relationship of cutaneous malignant melanoma to individual sunlight-exposure habits, J. Natl. Cancer Inst. 76: 403–414.
CAS
Google Scholar
Koh, H. K., 1991, Cutaneous melanoma, N. Engl. J. Med. 325: 171–182.
CrossRef
CAS
Google Scholar
Kuh, C., 1932, A study of vitamin A in relation to experimental cancer, Yale J. Biol. Med. 5: 123–126.
CAS
Google Scholar
Lambe, W., 1815, Water and Vegetable Diet in Consumption, Scrofula, Cancer, Asthma and other Chronic Diseases, Fowler & Wells, New York (1851); London edition (1815).
Google Scholar
Ley, R. D., Applegate, L. A., Padilla, R. S., and Stuart, T. D., 1989, Ultraviolet radiation-induced malignant melanoma in Monodelphis domestica, Photochem. Photobiol. 50: 1–5.
CrossRef
CAS
Google Scholar
McGrath, H., Wilson, W. A., and Scopelitis, E., 1986, Acute effects of low fluence ultraviolet light on T-lymphocyte subsets, Photochem. Photobiol. 43: 627–631.
CrossRef
CAS
Google Scholar
Magnus, I. A., Jarrett, A., Prankert, A. J., and Rimington, C., 1961, Erythropoietic protoporphyria: A new porphyria syndrome with solar urticaria due to protoporphyrinaemia, Lancet 2: 448–451.
CrossRef
CAS
Google Scholar
Makinodan, T., Lubinski, J., and Fong, T. C., 1987, Cellular, biochemical and molecular basis of T-cell senescence, Arch. Pathol. Lab. Med. 111: 910–914.
CAS
Google Scholar
Mathews-Roth, M. M., 1989, Beta carotene, canthaxanthin and phytoene, in: Nutrion and Cancer Prevention: Investigating the Role of Micronutrients (T. E. Moon and M. S. Micozzi, eds.), Dekker, New York, pp. 273–290.
Google Scholar
Mathews-Roth, M. M., Pathak, M. A., Fitzpatrick, T. B., et al., 1970, Beta carotene as a protective agent in erythropoietic protoporphyria, N. Engl. J. Med. 282: 1231–1234.
CrossRef
CAS
Google Scholar
Mathews-Roth, M. M., Pathak, M. A., Fitzpatrick, T. B., et al., 1974, Beta carotene as an oral photoprotective agent in erythropoietic protoporphyria, J. Am. Med. Assoc. 228: 1004–1008.
CrossRef
CAS
Google Scholar
Mathews-Roth, M. M., Pathak, M. A., Fitzpatrick, T. B., Harber, L. H., and Kass, E. H., 1977, Beta carotene therapy in erythropoietic protoporphyria and other photosensitivity diseases, Arch. Dermatol. 113: 1229–1232.
CrossRef
CAS
Google Scholar
Meydani, S. N., Barklund, M. P., Liu, S., Meydani, M., Miller, R. A., Cannon, J. G., Morrow, F. D., Rocklin, R., and Blumberg, J. B., 1990, Vitamin E supplementation enhances cell-mediated immunity in healthy elderly subjects, Am. J. Clin. Nutr. 52: 557–563.
CAS
Google Scholar
Moore, T., 1930, Vitamin A and carotene. VI. The conversion of carotene to vitamin A in vivo, Biochem. J. 24: 692–702.
CAS
Google Scholar
Morison, W. L., 1989, Effects of ultraviolet radiation on the immune system in humans, Photochem. Photobiol. 50: 515–524.
CrossRef
CAS
Google Scholar
MRC, 1949, Vitamin A requirement of human adults. An experimental study of vitamin A deprivation in man, MRC 264, HMSO, London, p. 23.
Google Scholar
Noonan, F. P., Kripke, M. L., Pederson, G. M., and Greene, M. I., 1981, Suppression of contact hypersensitivity by ultraviolet irradiation is associated with defective antigen presentation, Immunology 43: 527–533.
CAS
Google Scholar
Olcott, H. S., and McCann, D. C., 1931, Carotenase: The transformation of carotene to vitamin A in vitro, Science 74: 414.
CrossRef
CAS
Google Scholar
Olson, J. A., Carotenoids, vitamin A and cancer, J. Nutr. 116: 1127–1130.
Google Scholar
Olson, J. A., and Hayaishi, O., 1965, The enzymatic cleavage of beta carotene into vitamin A, Proc. Natl. Acad. Sci. USA 54: 1364–1369.
CrossRef
CAS
Google Scholar
Penn, N. D., Purkins, L., Kelleher, J., Heatley, R. V., Mascie-Taylor, B. H., and Belfield, P. W., 1991, The effect of dietary supplementation with vitamins A, C and E on cell-mediated immune function in elderly long-stay patients: A randomized controlled trial, Age Ageing 20: 169–174.
CrossRef
CAS
Google Scholar
Pesek, C. A., and Warthesen, J. J., 1987, Photodegradation of carotenoids in a vegetable juice system, J. Food Sci. 52: 744–746.
CrossRef
CAS
Google Scholar
Pesek, C. A., and Warthesen, J. J., 1988, Characterization of the photodegradation of beta-carotene in aqueous model systems, J. Food Sci. 53: 1517–1520.
CrossRef
CAS
Google Scholar
Peto, R., Doll, R., Buckley, J. D., and Sporn, M. B., 1981, Can dietary beta carotene materially reduce human cancer rates? Nature 290: 201–208.
Google Scholar
Prabhala, R. H., Maxey, V., Hicks, M. J., and Watson, R. R., 1989, Enhancement of the expression of activation markers on human peripheral blood mononuclear cells by in vitro culture with retinoids and carotenoids, J. Leukocyte Biol. 45: 249–254.
CAS
Google Scholar
Prabhala, R. H., Garewal, H. S., Hicks, M. J., Sampliner, R. E., and Watson, R. R. 1991, The effects of 13-cis-retinoic acid and beta-carotene on cellular immunity in humans, Cancer 67: 1556–1560.
CrossRef
CAS
Google Scholar
Richmond, A., and Thomas, H. G., 1988, Melanoma growth stimulatory activity: Isolation from human melanoma tumors and characterization of tissue distribution, J. Cell. Biochem. 36: 185–198.
CrossRef
CAS
Google Scholar
Roe, D. A., 1986, History of promotion of vegetable cereal diets, J. Nutr. 116: 1355–1363.
CAS
Google Scholar
Schoen, D. J., and Watson, R. R., 1988, Prevention of UV irradiation induced suppression of monocyte functions by retinoids and carotenoids in vitro, Photochem. Photobiol. 5: 659–663.
CrossRef
Google Scholar
Schwartz, T., Urbanska, A., Gschnait, F., and Luger, T. A., 1987, UV-irradiated epidermal cells produce a specific inhibitor of IL-1 activity, J. Immunol. 138: 1457–1463.
Google Scholar
Seifter, E., Rettura, G., and Levenson, S. M., 1981, Carotenoids and cell mediated immune responses, in: The Quality of Foods and Beverages (G. Charalambors and G. Inglett, eds.), Academic Press, New York, pp. 335–347.
CrossRef
Google Scholar
Seifter, E., Rettura, G., Padawer, J., and Levenson, S. M., 1982, Moloney murine sarcoma virus tumors in CBA/J mice: Chemopreventive and chemotherapeutic actions of supplemental beta carotene, Natl. Cancer Inst. 68: 835–840.
CAS
Google Scholar
Spellman, C. W., and Daynes, R. A., 1977, Modification of immunologic potential by ultraviolet radiation. II. Generation of suppressor cells in short term UV irradiated mice, Transplantation 24: 120–126.
CrossRef
CAS
Google Scholar
Stich, H. F., Mathew, B., Sankarayanan, R., and Krishnan Nair, M., 1991, Vitamin A and beta carotene: Long term protective effects in oral leukoplakia, in: Vitamins and Cancer Prevention (S. A. Laidlaw and M. E. Swendseid, eds.), Wiley-Liss, New York, pp. 15–24.
Google Scholar
Tomita, Y., Himeno, K., Momoto, K., Endo, H., and Hirohata, T., 1987, Augmentation of tumor immunity against syngeneic tumors in mice by beta carotene, J. Natl. Cancer Inst. 78: 679–681.
CAS
Google Scholar
Verma, A. K., 1991, Modulation of carcinogenesis by vitamin A and its analogs (retinoids), in: Vitamins and Cancer Prevention (S. A. Laidlaw and M. E. Swendseid, eds.), Wiley-Liss, New York, pp. 25–37.
Google Scholar
Walter, S. D., Marrett, L. D., From, L., Hertzman, C., Shannon, H. S., and Roy, P. 1990, The association of cutaneous malignant melanoma with the use of sunbeds and sunlamps, Am. J. Epidemiol. 131: 232–243.
CAS
Google Scholar
Wang, C. Q., Kripke, M. L., and Fidler, I. J., 1990, Ultraviolet-B-irradiated mouse epidermis releases mediators that stimulate melanoma cells, Photodermatol. Photoimmunol. Photomed. 7: 128–135.
CAS
Google Scholar
Watson, R. R., Prabhala, R. H., Plezia, P. M., and Alberts, D. S., 1991, Effects of beta-carotene on lymphocyte subpopulations in elderly humans: Evidence for a dose response relationship, Am. J. Clin. Nutr. 53: 90–94.
CAS
Google Scholar
White, W. S., Kim, C.-L, Kalkwarf, H. J., Bustos, P., and Roe, D. A., 1988, Ultraviolet light induced reductions in plasma carotenoid levels, Am. J. Clin. Nutr. 47: 879–883.
CAS
Google Scholar
Wolf, G., 1982, Is dietary beta carotene an anti-cancer agent? Nutr. Rev. 9: 257–261.
Google Scholar