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Biology of Salmonella pp 191–198Cite as

Colonization and Invasion of the Intestinal Tract by Salmonella

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Part of the book series: NATO ASI Series ((NSSA,volume 245))

Abstract

There are over 1,800 serotypes of Salmonella that are capable of colonizing and infecting a diversity of cold-blooded and warm-blooded animal hosts (LeMinor, 1984). Salmonella infection is a major cause of food-borne and water-borne illness (Hook, 1985) and leads to gastroenteritis, bacteremia, or enteric fever. S. enteritidis serotype typhimurium, S. choleraesuis and S. typhi, respectively, are most often studied as causing these three disease states. Although S. enteritidis and its 1,000 or more serovars are the principal cause of gastroenteritis in humans, most studies on pathogenesis have used the murine animal model in which the disease symptomology is more analogous to enteric fever caused by S. typhi in humans. Salmonella infection in rabbits constitutes a better system for studying the causes of gastroenteritis as reported by Stephens and colleagues (1985).

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Authors and Affiliations

  1. Department of Biology, Washington University, St. Louis, Missouri, 63130, USA

    Roy Curtiss III, David L. MacLeod, Hank A. Lockman, Jorge E. Galan, Sandra M. Kelly & Gregory G. Mahairas

  2. Department of Microbiology, State University of New York at Stony Brook, Stony Brook, New York, 11794, USA

    Jorge E. Galan

  3. Department of Microbiology & Immunology, University of North Carolina, Chapel Hill, North Carolina, 27599, USA

    Hank A. Lockman

Authors
  1. Roy Curtiss III
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  2. David L. MacLeod
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  3. Hank A. Lockman
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  4. Jorge E. Galan
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  5. Sandra M. Kelly
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  6. Gregory G. Mahairas
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Editor information

Editors and Affiliations

  1. New York Medical College, Valhalla, New York, USA

    Felipe Cabello

  2. Cambridge University, Cambridge, UK

    Carlos Hormaeche

  3. University of Messina, Messina, Italy

    Pasquale Mastroeni  & Letterio Bonina  & 

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© 1993 Springer Science+Business Media New York

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Curtiss, R., MacLeod, D.L., Lockman, H.A., Galan, J.E., Kelly, S.M., Mahairas, G.G. (1993). Colonization and Invasion of the Intestinal Tract by Salmonella . In: Cabello, F., Hormaeche, C., Mastroeni, P., Bonina, L. (eds) Biology of Salmonella . NATO ASI Series, vol 245. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2854-8_22

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  • DOI: https://doi.org/10.1007/978-1-4615-2854-8_22

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6236-4

  • Online ISBN: 978-1-4615-2854-8

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