Role of Catalysis on the Evolution of Error-Prone Self-Replicative Molecules
Nucleic acids are biological molecules that have intrinsic template activity by themselves, without the aid of any other molecular species. The behavior of populations of this kind of molecules is the main subject of a paper published by Eigen in the early seventies1. At that time, some experiments were carried out in order to find out what the dynamics of these systems was like2. Just at the beginning, the mathematical model agrees with biological experiments in relation to the general behavior of these systems. This fact caused Eigen’s model to be seriously taken into account and deeply analyzed.
Unable to display preview. Download preview PDF.
- 12.P. Tarazona, Contribution to this volume.Google Scholar
- 13.P. Schuster, in ‘Molecular Evolution on Rugged landscapes: Proteins, RNA and The Inmune System’, Ed. A.S. Perelson and S.A. Kauffman, 47 (1991).Google Scholar
- 14.M. Eigen and P. Schuster, ‘The hypercycle-A principle of natural self-organization’, Springer Verlag, Berlin (1979).Google Scholar
- 15.J. Hofbauer and K. Sigmund, ‘The Theory of Evolution and Dynamical Systems’. Cambridge University Press, Cambridge (1988).Google Scholar
- 16.P. Schuster, in ‘Molecular Evolution on Rugged landscapes: Proteins, RNA and The Inmune System’, Ed. A.S. Perelson and S.A. Kauffman, 281 (1991).Google Scholar
- 21.J.C. Nuño, M. Andrade, F. Morán and F. Montero, Bull. Math. Biol. 55, 385 (1993).Google Scholar
- 22.J.C. Nuño, M. Andrade and F. Montero, Bull.Math.Biol. 55, 417 (1993).Google Scholar
- 23.J.C. Nuño and P. Tarazona, submitted to Theor.Pop.Biol. (1992).Google Scholar
- 24.B.M.R. Stadler and P.F. Stadler, Bull.Math.Biol 53, 469 (1991).Google Scholar