Role of Catalysis on the Evolution of Error-Prone Self-Replicative Molecules

  • F. Montero
  • J. C. Nuño
Part of the NATO ASI Series book series (NSSB, volume 304)


Nucleic acids are biological molecules that have intrinsic template activity by themselves, without the aid of any other molecular species. The behavior of populations of this kind of molecules is the main subject of a paper published by Eigen in the early seventies1. At that time, some experiments were carried out in order to find out what the dynamics of these systems was like2. Just at the beginning, the mathematical model agrees with biological experiments in relation to the general behavior of these systems. This fact caused Eigen’s model to be seriously taken into account and deeply analyzed.


Catalytic Activity Sequence Space Fitness Landscape Catalytic Constant Mutation Matrix 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • F. Montero
    • 1
  • J. C. Nuño
    • 2
  1. 1.Dpto. de Bioquímica y Biología Molecular IFac. CC. Químicas Universidad ComplutenseMadridSpain
  2. 2.Dpto. de MatemáticasE.T.S.I. de Montes Universidad PolitécnicaMadridSpain

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