Amphibian Opioids: Novel Dermorphin-Like Peptides

  • Lucia Negri
Chapter
Part of the GWUMC Department of Biochemistry and Molecular Biology Annual Spring Symposia book series (GWUN)

Abstract

Among the fourteen peptide families so far described in amphibian skin, that of the opioid peptides is certainly one of the most interesting, as it raises a number of fascinating problems in the field of biochemistry, pharmacology and molecular biology. Opioid peptides have been so far found only in the skin of South American hylid frogs belonging to the subfamily Phyllomedusinae. These are heptapeptides with the common amino-terminal sequence Tyr-D-Xaa-Phe, where D-Xaa is either D-alanine or D-methionine.

Keywords

Codon Acetonitrile Morphine Methionine Naloxone 

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Copyright information

© Plenum Press, New York 1993

Authors and Affiliations

  • Lucia Negri
    • 1
  1. 1.Institute of Medical PharmacologyUniversity “La Sapienza”RomeItaly

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