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The Role of Somatostatin Receptors in the Diagnosis and Therapy of Cancer

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Growth Factors, Peptides and Receptors

Abstract

Somatostatin (SS) is a representative member of the family of small regulatory peptides which are often characterised by a wide spectrum of actions in various organs of the human body. One of the most prominent and well-documented roles of SS is its inhibition of hormone secretory processes, in particular in the pituitary (GH, TSH) and in the gastroenteropancreatic (GEP) system (Insulin, Glucagon, ViP, Secretin, etc...)1. In addition, SS can modulate the neurotransmission in various brain regions1. All these SS actions seem to be mediated through specific SS receptors (SS-R)2.

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© 1993 Plenum Press, New York

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Reubi, J.C., Krenning, E., Lambert, S.W. (1993). The Role of Somatostatin Receptors in the Diagnosis and Therapy of Cancer. In: Moody, T.W. (eds) Growth Factors, Peptides and Receptors. GWUMC Department of Biochemistry and Molecular Biology Annual Spring Symposia. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2846-3_43

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  • DOI: https://doi.org/10.1007/978-1-4615-2846-3_43

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-306-44484-5

  • Online ISBN: 978-1-4615-2846-3

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