Abstract
This article describes a nerve simulation program, called “NEURON”, developed in collaboration with John W. Moore at Duke University. NEURON was designed for two kinds of problems: 1) where cable properties of cells play an important role, possibly including extracellular potential close to the membrane, and 2) where cell membrane properties are complex, involving many ion-specific channels and ion accumulation. NEURON can be used to simulate networks of neurons but since the user interface does not have network specific syntax this is only appropriate when the network contains neurons involving electrotonic spread of current or complex membrane response properties.
Keywords
- Order Method
- Area Node
- Cable Equation
- Membrane Mechanism
- Cell Membrane Property
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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References
Douglas, J. (1961). A survey of numerical methods for parabolic differential equations. In: Advances in Computers, Vol. II. Ch 1. F. Alt. (ed.) Academic Press, New York.
Hines, M. (1984). Efficient computation of branched nerve equations. Int. J. of Biomed. Computing. 15: 69–76.
Hines, M. (1992). NEURON — A program for simulation of nerve equations. In: Neural Systems: Analysis and Modeling 2. F. Eeckman (ed.) Kluwer Academic Publishers, Norwell, MA.
Hines, M. (1993). Third order spatially correct simulation of neuron cable equations. (submitted).
Kernighan, B.W. and Pike, R. (1984). The Unix Programming Environment. Prentice hall, Englewood Cliffs, New Jersey.
Kohn, M. C., Hines, M., Kootsey, J. M., and Feezor, M. D. (1992). A block organized model builder. In: Advances in Mathematics and Computers in Medicine v.6., D. Mikulecky and M. Witten (eds.), Pergamon Press, New York.
Linton, M., Vlissides, J, and Calder, P. (1989). Composing user interfaces with InterViews. IEEE Computer 22. February.
MacGregor, R. (1987) Neural and Brain Modeling Ch. 14, Academic Press, New York.
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© 1994 Springer Science+Business Media New York
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Hines, M. (1994). The Neuron Simulation Program. In: Skrzypek, J. (eds) Neural Network Simulation Environments. The Kluwer International Series in Engineering and Computer Science, vol 254. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2736-7_8
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DOI: https://doi.org/10.1007/978-1-4615-2736-7_8
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-6180-0
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