Sensitivity in the Response of Piriform Pyramidal cells to Fluctuations in Synaptic Timing
Current source density analysis has revealed a stereotyped pattern of synaptic input in the pyramidal cells of the piriform cortex in rat and opossum which is believed to underlie activity in the awake behaving animals as well. A realistic simulation of a piriform pyramidal cell was constructed in order to examine how fluctuations in synaptic timing affect cell response. Results indicate that cell response is considerably resilient to fluctuations in synaptic timing near physiological values.
KeywordsNMDA Editing GABA Biocytin
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