Repeat resections for recurrent colorectal liver metastases

  • Bernard Nordlinger
  • J.-C. Vaillant
Part of the Cancer Treatment and Research book series (CTAR, volume 69)


The 5-year survival rate after surgical resection of colorectal liver metastases is close to 25% and ranges from 16% to 45% [1–13]. On the other hand, few patients with unresected colorectal liver metastases survive 5 years [14–16]. Unfortunately, tumors recur in 60–70% of patients during the years or even months following liver resections [6,8,11,17–22]. About half of these recurrences are located in the liver [8,23] but most of them are diffuse and unresectable. Ten to 55% of the recurrences are isolated in the liver without extrahepatic involvement [2,4,6,8,9,11,17–26]. However, a small percent of them are theoretically resectable according to their size, location, and relations with vessels. Two questions should be answered to determine the validity of repeat resections of recurrent liver metastases:
  1. 1.

    Is their operative risk higher than in primary liver resections?

  2. 2.

    What are the long-term results? Most published series are retrospective and do not exceed 10–15 patients. Recently, a French multicentric study [23] collected data from more than 100 patients who had undergone repeat liver resections, 15 of them having received three liver resections.



Liver Metastasis Liver Resection Hepatic Resection Colorectal Liver Metastasis Colorectal Metastasis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media Dordrecht 1994

Authors and Affiliations

  • Bernard Nordlinger
  • J.-C. Vaillant

There are no affiliations available

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